Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine Renske van Delft, Danielle Lambrechts,

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Presentation transcript:

Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine Renske van Delft, Danielle Lambrechts, Pauline Verschuure, Jacques Hulsman, Marian Majoie Seizure - European Journal of Epilepsy Volume 19, Issue 1, Pages 36-39 (January 2010) DOI: 10.1016/j.seizure.2009.10.009 Copyright © 2009 British Epilepsy Association Terms and Conditions

Fig. 1 Ketone formation. Ketones are formed when acetyl-CoA is not able to enter the Krebs Cycle. Seizure - European Journal of Epilepsy 2010 19, 36-39DOI: (10.1016/j.seizure.2009.10.009) Copyright © 2009 British Epilepsy Association Terms and Conditions

Fig. 2 BHB concentration related to reduction at 3 months. Seizure - European Journal of Epilepsy 2010 19, 36-39DOI: (10.1016/j.seizure.2009.10.009) Copyright © 2009 British Epilepsy Association Terms and Conditions

Fig. 3 BHB concentration related to reduction at 6 months. Seizure - European Journal of Epilepsy 2010 19, 36-39DOI: (10.1016/j.seizure.2009.10.009) Copyright © 2009 British Epilepsy Association Terms and Conditions

Fig. 4 Ketones in urine (average) related to reduction at 3 months. Spearman rank: R=0.10, p=0.32. Seizure - European Journal of Epilepsy 2010 19, 36-39DOI: (10.1016/j.seizure.2009.10.009) Copyright © 2009 British Epilepsy Association Terms and Conditions

Fig. 5 Ketones in urine (average) related to reduction at 6 months. Spearman rank: R=0.09, p=0.36. Seizure - European Journal of Epilepsy 2010 19, 36-39DOI: (10.1016/j.seizure.2009.10.009) Copyright © 2009 British Epilepsy Association Terms and Conditions