Figure 2 A patient with aortic stenosis and mitral regurgitation

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Figure 2 A patient with aortic stenosis and mitral regurgitation Figure 2 | A patient with aortic stenosis and mitral regurgitation. a | This patient has severe, symptomatic aortic stenosis with a mean transaortic gradient of 48 mmHg and an aortic valve area of 0.7 cm2 on Doppler echocardiography. Left ventricular ejection fraction is 45%. b | Colour Doppler shows that moderate-to-severe mitral regurgitation is also present (see Supplementary information S1 (video)). c,d | The same patient, 6 months after transcatheter aortic valve implantation. The mean transaortic pressure gradient is 11 mmHg with only mild residual mitral regurgitation (see Supplementary information S2 (video)). Left ventricular ejection fraction is 65%. Unger, P. et al. (2016) Pathophysiology and management of multivalvular disease Nat. Rev. Cardiol. doi:10.1038/nrcardio.2016.57