HSV‐1 depletes mt DNA and mt mRNA in infected Vero cells.

Slides:



Advertisements
Similar presentations
Invest. Ophthalmol. Vis. Sci ;50(6): doi: /iovs Figure Legend:
Advertisements

From: An Investigative Peptide–Acyclovir Combination to Control Herpes Simplex Virus Type 1 Ocular Infection Invest. Ophthalmol. Vis. Sci ;54(9):
Ann Intern Med. 1995;122(12): doi: / Figure Legend:
Accumulation of transcripts from MULE‐F19G14–CyP40 and transposons in mom1 and ddm1. Accumulation of transcripts from MULE‐F19G14–CyP40 and transposons.
Induction of mPer1 mRNA expression by prostaglandin E2 (PGE2) in NIH3T3 cells. Induction of mPer1 mRNA expression by prostaglandin E2 (PGE2) in NIH3T3.
Statistical analysis of transgene expression in pigs generated by lentiviral gene transfer. Statistical analysis of transgene expression in pigs generated.
Expression of adenylyl cyclases and miR‐142‐3p in CD4+CD25− T cells and CD4+CD25+ regulatory T cells. Expression of adenylyl cyclases and miR‐142‐3p in.
Cdc42.GTP directly activates PAK4.
Amyloid‐associated gliosis in APPPS1‐21 transgenic mice.
Nur77 interacts with COUP‐TF in yeast.
Origin‐fork purification.
REF and ATP5b status on mitochondrial fraction.
Increased proliferation and delayed differentiation of adult primary myoblasts derived from MyoDR99,102 mice. Increased proliferation and delayed differentiation.
Vav‐1 gene‐targeting strategy.
Expression of Hoxa9 and Meis1a in spleen cells isolated from leukemic recipients of Hoxa9‐ and Meis1a‐transduced bone marrow cells. Expression of Hoxa9.
Telomerase activity in smooth‐muscle cells increases lifespan and extends telomeres. Telomerase activity in smooth‐muscle cells increases lifespan and.
The cyclin B1 promoter is accessible to restriction endonucleases in vivo. The cyclin B1 promoter is accessible to restriction endonucleases in vivo. Nuclei.
Yeast containing pICC10 (Tir) and pICC267 (CK18) and pTY474S and pICC267 demonstrated an approximately 12.5‐fold increase in β‐galactosidase activity compared.
Expression analyses of KLK7 mRNA in the brains of AD patients
Accumulation of 2,4‐dienoyl‐CoA ester (C22:7) during β‐oxidation of docosahexaenoic acid (C22:6). Accumulation of 2,4‐dienoyl‐CoA ester (C22:7) during.
1,25‐dihydroxyvitamin D3 and retinoic acid induce p19ink4d expression.
Loss of USP8 or HIF1α impairs endocytic recycling required for ciliogenesis Kinetic analysis of transferrin recycling measured by flow cytometry. Loss.
Calcium regulates ERK nuclear association, but not its activation.
SWP RNA expression pattern.
Synthetic view of genome‐wide mRNA profile changes induced by toxic GSH levels and GSH depletion. Synthetic view of genome‐wide mRNA profile changes induced.
Measurement of terminal restriction fragments (TRFs) in bone marrow cells from both parents and the G4 progeny. Measurement of terminal restriction fragments.
Import of NH‐Idp3p‐, PTS‐1 (3HAD)‐ and PTS2 (3‐ketoacyl‐CoA thiolase)‐containing proteins in wild‐type, Δpex5 and Δpex7 cells. Import of NH‐Idp3p‐, PTS‐1.
TRF2ΔBΔM induces apoptosis and senescence in the mouse liver.
Transcriptional activity of the exogenous cyclin B1 promoter is high in the G2/M phases of the cell cycle. Transcriptional activity of the exogenous cyclin.
Location of IL‐17‐producing cell types.
Interaction of xFRS2 with the Src family kinase Laloo.
Characterization and phenotypes of sima mutants.
Deiminated REF in regulation of ATP synthase expression.
Consequences of T‐DNA insertion on SWP expression in swp mutant.
Circadian gene expression induced by prostaglandin E2 (PGE2) in NIH3T3 cells. Circadian gene expression induced by prostaglandin E2 (PGE2) in NIH3T3 cells.
Ubiquitination of Drp1 by MARCH‐V.
Volume 18, Issue 6, Pages (December 2015)
The mRNA stem cell signature.
RNA charging levels before and after starvation.
Mutations affecting HOIP–UBA and HOIL‐1L–UBL interaction that compromise NF‐κB activation. Mutations affecting HOIP–UBA and HOIL‐1L–UBL interaction that.
Analysis of WHITE COLLAR 2 isoforms.
The MSP domain of MOSPD2 is sufficient to interact with STARD3 and STARD3NL The MSP domain of MOSPD2 is sufficient to interact with STARD3 and STARD3NL.
Prevention of Genital Herpes Simplex Virus Type 1 and 2 Disease in Mice Immunized with a gD-Expressing Dominant-Negative Recombinant HSV-1  Richard Brans,
Beclin‐1 depletion reduces targeting of several outer kinetochore proteins. Beclin‐1 depletion reduces targeting of several outer kinetochore proteins.
Brian Yordy, Norifumi Iijima, Anita Huttner, David Leib, Akiko Iwasaki 
Expression of bnl in mesodermal bridge‐cells.
Zc3h10 overexpression boosts mitochondrial function and density in myotubes Zc3h10 overexpression boosts mitochondrial function and density in myotubes.
Zc3h10 downregulation impairs mitochondrial function and C2C12 differentiation Zc3h10 downregulation impairs mitochondrial function and C2C12 differentiation.
System approaches to analyze the effects of Zc3h10 knockdown
Volume 61, Issue 1, Pages S3-S8 (January 2002)
Ssu72 is required for telomeric C‐strand stability
Nicotinamide riboside (NR) induces mitochondrial biogenesis and effectively ameliorates morphological and genetic landmarks of mitochondrial myopathy ASkeletal.
Downregulation of human SSU72 results in telomere elongation and fragility Downregulation of human SSU72 results in telomere elongation and fragility Telomere.
Ssu72 is required for polymerase α activation
Effect of the loss of Kar4 on the induction of various promoters
Incorporation of the B18R Gene of Vaccinia Virus Into an Oncolytic Herpes Simplex Virus Improves Antitumor Activity  Xinping Fu, Armando Rivera, Lihua.
Richard A Voit, Moira A McMahon, Sara L Sawyer, Matthew H Porteus 
Francis Crick's central dogma of biology revolves around the transcription of mRNA from DNA, the translation of proteins from mRNA, and the degradation.
High‐throughput screen to identify a new regulator of mitochondrial function High‐throughput screen to identify a new regulator of mitochondrial function.
Heat shock during translation of an aberrant mitochondrial mRNA activates OMA1 and a ribosome decay pathway. Heat shock during translation of an aberrant.
ZBTB48 is required for MTFP1 expression
The CHCH domain is necessary for mitochondrial import of CHCHD10
Volume 18, Issue 5, Pages (May 2010)
CagA is required for Helicobacter pylori‐induced activation of NF‐κB.
Rebecca I Montgomery, Morgyn S Warner, Brian J Lum, Patricia G Spear 
Expression of Hox genes, ALK5, GDF11 and ALK4 in Alk5−/− mutants.
Glucose uptake and expression of thermogenesis markers are increased in the BAT of HFD-fed NprcAKO mice. Glucose uptake and expression of thermogenesis.
Dnmt2 mutants show delayed immune responses and Dnmt2–EGFP relocalizes and interacts with DCV RNA during infection. Dnmt2 mutants show delayed immune responses.
Immunization with a Dominant-Negative Recombinant HSV Type 1 Protects against HSV-1 Skin Disease in Guinea Pigs  Richard Brans, Elof Eriksson, Feng Yao 
Innate Immune Recognition of mtDNA—An Undercover Signal?
Presentation transcript:

HSV‐1 depletes mt DNA and mt mRNA in infected Vero cells. HSV‐1 depletes mt DNA and mt mRNA in infected Vero cells. Mt mRNA (A) and mt DNA (B) were monitored by northern and Southern blot hybridization, respectively, by using probes for COX2 and ND6. Infections with the indicated HSV‐1 strains (10 PFU/cell) were allowed to proceed for 4, 8 and 12 h. Mt mRNA (C) and mt DNA (D) loss in Vero cells and 6‐5 cells that express UL12 after HSV infection. COX2, cytochrome c oxidase subunit II; HSV‐1, herpes simplex virus type 1; mt, mitochondrial; ND6, nicotinamide adenine dinucleotide dehyrogenase subunit 6; PFU, plaque forming unit; WT, wild type. Holly A Saffran et al. EMBO Rep. 2007;8:188-193 © as stated in the article, figure or figure legend