Street View of the Cognitive Map

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Street View of the Cognitive Map Cian O’Donnell, Terrence J. Sejnowski  Cell  Volume 164, Issue 1, Pages 13-15 (January 2016) DOI: 10.1016/j.cell.2015.12.051 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 Hippocampal Neurons in a Real-World Environment and in Virtual Reality (A) Schematic diagram of experimental recording set up. A rat is allowed to explore either a circular platform in the real world (left) or on a rotatable ball in virtual reality while head-fixed (right). (B) Firing properties from one example neuron recorded while the rat explores in the real world (left) and another example neuron recorded in the virtual reality setup (right). The black circles represent the spatial environment the rat could explore, and colored dots represent the locations that the rat occupied when the neuron fired. The open circles represent the directional tuning curve of the same cells in polar co-ordinates. Figure adapted from Acharya et al. (2016), Figures 1 and 2. (C) Schematic diagram of the approximate relative proportions of hippocampal CA1 neurons showing spatial tuning (green), directional tuning (magenta), conjunctive tuning (green and magenta), or no tuning (white) in the real world (left) and virtual reality (right) experiments. Cell 2016 164, 13-15DOI: (10.1016/j.cell.2015.12.051) Copyright © 2016 Elsevier Inc. Terms and Conditions