Volume 98, Issue 1, Pages 243-245 (July 1990) Rapidly Progressive Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome  Naohisa Tsunoda, M.D., Tomoaki Iwanaga, M.D., Tatsuya Saito, M.D., Satoshi Kitamura, M.D., F.C.C.P., Ken Saito, M.D.  CHEST  Volume 98, Issue 1, Pages 243-245 (July 1990) DOI: 10.1378/chest.98.1.243 Copyright © 1990 The American College of Chest Physicians Terms and Conditions

Figure 1 Anteroposterior view of chest, showing slightly hyperinflated lungs with no significant opacities. Roentgenogram was taken 24 days after onset of Stevens-Johnson syndrome when progressive dyspnea developed. CHEST 1990 98, 243-245DOI: (10.1378/chest.98.1.243) Copyright © 1990 The American College of Chest Physicians Terms and Conditions

Figure 2 Obstruction of large bronchus by fibrous scar tissue. Luminal space is totally replaced by fibrous tissue. Other bronchial mucosal components, such as elastic fiber layer (arrow), smooth muscle layer, and cartilage, are preserved (EVG, original magnification × 120) CHEST 1990 98, 243-245DOI: (10.1378/chest.98.1.243) Copyright © 1990 The American College of Chest Physicians Terms and Conditions

Figure 3 Membranous obliteration of large bronchus. Proximal part (right lumen) preserves almost normal mucosal structure. On the other hand, distal part (left lumen) exhibits narrowing of lumen and proliferation of granulation tissue on luminal surface (arrow) (HE, original magnification × 40). CHEST 1990 98, 243-245DOI: (10.1378/chest.98.1.243) Copyright © 1990 The American College of Chest Physicians Terms and Conditions