Impact of Lung Function Changes After Induction Radiochemotherapy on Resected T4 Non-Small Cell Lung Cancer Outcome Jean Perentes, MD, PhD, Sabina Bopp,

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Impact of Lung Function Changes After Induction Radiochemotherapy on Resected T4 Non-Small Cell Lung Cancer Outcome Jean Perentes, MD, PhD, Sabina Bopp, MD, Thorsten Krueger, MD, Michel Gonzalez, MD, Pierre-Yves Jayet, MD, Alban Lovis, MD, Oscar Matzinger, MD, Christiane Ruffieux, PhD, Hans-Beat Ris, MD, Igor Letovanec, MD, Solange Peters, MD, PhD The Annals of Thoracic Surgery Volume 94, Issue 6, Pages 1815-1822 (December 2012) DOI: 10.1016/j.athoracsur.2012.08.054 Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Survival is shown according to completeness of resection. Patients with complete resection (solid line) had a significantly better 5-year survival than those with incomplete resection (dashed line; p = 0.004). The Annals of Thoracic Surgery 2012 94, 1815-1822DOI: (10.1016/j.athoracsur.2012.08.054) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Survival is shown according to extent of resection. Patients with pneumonectomy (dashed line) had a significantly worse 5-year survival than those with lobectomy (solid line; p = 0.01). The Annals of Thoracic Surgery 2012 94, 1815-1822DOI: (10.1016/j.athoracsur.2012.08.054) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Survival is shown according to postinduction pulmonary function changes for patients with (solid line) and without (dashed line) loss of (A) forced expiratory volume in 1 second (FEV1) (% predicted), and (B) diffusion capacity of the lung for carbon monoxide (Dlco; % predicted). There was no significant correlation with 5-year survival and postinduction FEV1 or Dlco changes. The Annals of Thoracic Surgery 2012 94, 1815-1822DOI: (10.1016/j.athoracsur.2012.08.054) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions