Trigger delays and leaks. Trigger delays and leaks. Inspiratory time with the 10 ventilators tested under 3 conditions: in the absence of leaks and with the noninvasive ventilation (NIV) algorithm deactivated (L0NIV0), in the presence of leaks and with the NIV algorithm deactivated (L+NIV0), and in the presence of leaks and with the NIV algorithm activated (L+NIV+). All results are pooled. Histogram bars are mean ± SD. * P < .05 vs L0NIV0; † P < .05 vs L+NIV0 (analysis of variance). Laurence Vignaux et al. Respir Care 2014;59:1463-1475 (c) 2012 by Daedalus Enterprises, Inc.