Studies of hypoxemic/reoxygenation injury: With aortic clamping

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Presentation transcript:

Studies of hypoxemic/reoxygenation injury: With aortic clamping Kai Ihnken, MDa, Kiyozo Morita, MDa, Gerald D. Buckberg, MDa, Michael P. Sherman, MDb, Louis J. Ignarro, PhDc, Helen H. Young, PhDa The Journal of Thoracic and Cardiovascular Surgery Volume 110, Issue 4, Pages 1274-1286 (October 1995) DOI: 10.1016/S0022-5223(95)70014-5 Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 1 Percent of recovery of Ees in control studies with CPB without hypoxemia (no hypoxemia) and after uncontrolled reoxygenation (ReO 2 ). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 1274-1286DOI: (10.1016/S0022-5223(95)70014-5) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 2 Percent recovery of Ees after controlled cardiac reoxygenation with KCI blood cardioplegia (KCI only) or with blood cardioplegia containing low calcium (low Ca ++), glutamate (G/A), and alkalosis (pH 7.6). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 1274-1286DOI: (10.1016/S0022-5223(95)70014-5) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 3 Mycardial No production during blood cardioplegic induction in controlled studies of CPB without hypoxemia and after uncontrolled reoxygenation reoxygenation (ReO2). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 1274-1286DOI: (10.1016/S0022-5223(95)70014-5) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 4 Mycardial •NO production during cardioplegic induction after controlled cardiac reoxygenation with KCI blood cardioplegia (KCI only) or with blood cardioplegia containing low calcium (low Ca++) glutamate/aspartate (G/A), and alkalosis (ph 7.6). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 1274-1286DOI: (10.1016/S0022-5223(95)70014-5) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 5 Mycardial conjugated diene during cardioplegic induction in control studies of CPB without hypoxemia, and after uncontrolled reoxygenation (ReO 2 ). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 1274-1286DOI: (10.1016/S0022-5223(95)70014-5) Copyright © 1995 Mosby, Inc. Terms and Conditions

Fig. 6 Mycardial conjugated diene (CD) production during cardioplegic induction after controlled cardiac reoxygenation with KCI blood cardioplegia (KCI only) or blood cardioplegia containing low calcium (low CA++), glutamate/aspartate (G/A), and alkalosis (pH 7.6). The Journal of Thoracic and Cardiovascular Surgery 1995 110, 1274-1286DOI: (10.1016/S0022-5223(95)70014-5) Copyright © 1995 Mosby, Inc. Terms and Conditions