Antidepressant Drugs Journal of Pain and Symptom Management

Slides:



Advertisements
Similar presentations
Treatment of postherpetic neuralgia: a review of therapeutic options Charles E. Argoff, MD, Nathaniel Katz, MD, Miroslav Backonja, MD Journal of Pain and.
Advertisements

Spinal Cord and Peripheral Nerve Stimulation Techniques for Neuropathic Pain Oscar A. de Leon-Casasola, MD Journal of Pain and Symptom Management Volume.
Palliative Medicine Fellowship: A Study of Resident Choices
Practical Dyspnea Assessment: Relationship Between the 0–10 Numerical Rating Scale and the Four-Level Categorical Verbal Descriptor Scale of Dyspnea Intensity 
Eva K. Schildmann, MD, Andrew N. Davies, FRCP 
Randomized Controlled Pilot Study of Neuromuscular Electrical Stimulation of the Quadriceps in Patients with Non-Small Cell Lung Cancer  Matthew Maddocks,
Chronic Pain Management in Older Adults: Special Considerations
Anxiety After Diagnosis Predicts Lung Cancer–Specific and Overall Survival in Patients With Stage III Non–Small Cell Lung Cancer: A Population-Based Cohort.
The Public Health Strategy for Palliative Care
Ketamine* Journal of Pain and Symptom Management
A Case Series of Patients Using Medicinal Marihuana for Management of Chronic Pain Under the Canadian Marihuana Medical Access Regulations  Mary E. Lynch,
Oral Candidosis in Community-Based Patients with Advanced Cancer
Opioids for Cancer Breakthrough Pain: A Pilot Study Reporting Patient Assessment of Time to Meaningful Pain Relief  Giovambattista Zeppetella, FRCP  Journal.
Accuracy of a Diagnostic Algorithm to Diagnose Breakthrough Cancer Pain as Compared With Clinical Assessment  Katherine Webber, MBBS, MSc, PhD, Andrew.
Definition, Categorization, and Terminology of Episodic Breathlessness: Consensus by an International Delphi Survey  Steffen T. Simon, MD, MSc, Vera Weingärtner,
Why Now? Timing and Circumstances of Hastened Deaths
Managing the Symptoms of Neuropathic Pain: An Exploration of Patients' Experiences  S. José Closs, BSc, RGN, MPhil, PhD, Vicki Staples, BSc, MSc, Innes.
Mary V. Callaway, MME, Stephen R. Connor, PhD, Kathleen M. Foley, MD 
Optimization of opioid therapy for preventing incident pain associated with bone metastases  Sebastiano Mercadante, MD, Patrizia Villari, MD, Patrizia.
Guided Imagery for Non-Musculoskeletal Pain: A Systematic Review of Randomized Clinical Trials  Paul Posadzki, PhD, Wendy Lewandowski, PhD, APRN, BC,
Randomized Controlled Pilot Study of Neuromuscular Electrical Stimulation of the Quadriceps in Patients with Non-Small Cell Lung Cancer  Matthew Maddocks,
What Palliative Care-Related Problems Do Patients Experience at HIV Diagnosis? A Systematic Review of the Evidence  Victoria M. Simms, MSc, Irene J. Higginson,
What Influences Patients’ Decisions on Artificial Hydration at the End of Life? A Q- Methodology Study  Catherine Malia, MSc, Michael I. Bennett, MB, ChB,
Use of Ketamine for Ischemic Pain in End-Stage Renal Failure
A Case of Visceral Post-Stroke Pain
Trends and Racial Differences in the Use of Androgen Deprivation Therapy for Metastatic Prostate Cancer  April P. Carson, PhD, Daniel L. Howard, PhD,
Andrew Davies, FRCP, Katherine Webber, PhD 
Barbara Gomes, MSc, Richard Harding, PhD, Kathleen M
Nocturnal Hypoxemia in Patients with Cancer
What Can We Learn About the Spiritual Needs of Palliative Care Patients From the Research Literature?  Mark Cobb, MA, Christopher Dowrick, MD, FRCGP,
Jane Gibbins, MBChB, MRCP, Rachel McCoubrie, MBBS, MRCP, MSc, Adrian H
Acetaminophen (Paracetamol)
David Clark, PhD, Michael Wright, PhD 
Redefining Appropriate Treatment Expectations
Xerostomia in Patients with Advanced Cancer
Amy Z. Boelk, PhD, MSSW, Betty J. Kramer, PhD, MSSW 
Integrating Palliative Care into National Policies
Karen Robb, PhD, MCSP, Stephen G. Oxberry, MRCP, Michael I
Documentation Quality of Inpatient Code Status Discussions
Jodi L. Hannan, MD, Steven M. Radwany, MD, Terry Albanese, PhD 
Katherine Webber, MBBS, MSc, PhD, Andrew N. Davies, FRCP, Martin R
Evaluation of Methadone Absorption After Topical Administration to Hospice Patients  Robert K. Sylvester, PharmD, Caroline Schauer, RN, John Thomas, MD,
Research Priorities in Health Economics And Funding for Palliative Care: Views of an International Think Tank  Richard Harding, BSc (Joint Hons), MSc,
A Systematic Review of Strategies Used to Increase Recruitment of People With Cancer or Organ Failure Into Clinical Trials: Implications for Palliative.
A Comparison of Symptom Prevalence in Far Advanced Cancer, AIDS, Heart Disease, Chronic Obstructive Pulmonary Disease and Renal Disease  Joao Paulo Solano,
Barrie R. Cassileth, PhD, Andrew J. Vickers, PhD 
Robert L. Jayes, MD, Robert M. Arnold, MD, Erik K. Fromme, MD 
Ketamine* Journal of Pain and Symptom Management
Antonio T. Fernando, MD, Nathan S. Consedine, PhD 
The Prevalence of Nocturnal Hypoxemia in Advanced Cancer
Rifampin (INN Rifampicin)
Development and Reliability Testing of the Victoria Bowel Performance Scale (BPS)  G. Michael Downing, MD, Craig Kuziemsky, PhD, Mary Lesperance, PhD,
William Shomali, MD  Journal of Pain and Symptom Management 
Carmen R. Green, MD, Laura Montague, BS, Tamera A. Hart-Johnson, MS 
Systematic Review of the Primary Research on Minority Ethnic Groups and End-of-Life Care From the United Kingdom  Natalie Evans, BSc, MSc, Arantza Meñaca,
Dylan G. Harris, MBBCh (Hons), MRCP, DipPallMed, Simon I. R
Missed Opportunities: A Mixed-Methods Analysis of CAM Discussions and Practices in the Management of Pain in Oncology  Aaron L. Leppin, MD, MSc, Cara.
Practical Dyspnea Assessment: Relationship Between the 0–10 Numerical Rating Scale and the Four-Level Categorical Verbal Descriptor Scale of Dyspnea Intensity 
Metastatic Acetabular Fractures: Evaluation and Approach to Management
Descriptors of Breathlessness in Patients With Cancer and Other Cardiorespiratory Diseases  Andrew Wilcock, DM, FRCP, Vincent Crosby, MRCGP, Andrew Hughes,
Logan H. Ramsey, BS  Journal of Pain and Symptom Management 
Anti-epileptic Drugs Journal of Pain and Symptom Management
Novel Use of Amantadine: To Treat Hiccups
Amy P. Abernethy, MD  Journal of Pain and Symptom Management 
Identification of Factors Associated With Fatigue in Advanced Cancer: A Subset Analysis of the European Palliative Care Research Collaborative Computerized.
Katherine Webber, MBBS, Andrew N
Bassam Estfan, MD, Declan Walsh, MSc, FACP, FRCP (Edin) 
Associations Between Physical Activity and Quality of Life in Cancer Patients Receiving Palliative Care: A Pilot Survey  Sonya S. Lowe, MD, MSc, Sharon.
Physical Activity Behaviors in Individuals with Multiple Sclerosis: Roles of Overall and Specific Symptoms, and Self-Efficacy  Erin M. Snook, MS, Robert.
Papiya B. Russell, BSc, MBChB, MRCP, Sarah C
Presentation transcript:

Antidepressant Drugs Journal of Pain and Symptom Management Paul Howard, BMedSci, MRCP, Robert Twycross, DM, FRCP, John Shuster, MD, Mary Mihalyo, BS, PharmD, RPh, Andrew Wilcock, DM, FRCP  Journal of Pain and Symptom Management  Volume 44, Issue 5, Pages 763-783 (November 2012) DOI: 10.1016/j.jpainsymman.2012.09.001 Copyright © 2012 Terms and Conditions

Fig. 1 Predominant mechanism of action of antidepressants. aMonoamine oxidase type A breaks down serotonin, norepinephrine (noradrenaline) and dopamine. Type B breaks down dopamine. Antidepressant-MAOIs are either non-selective (e.g., phenelzine) or type A selective (e.g., moclobemide). Antiparkinsonian MAOIs (e.g., selegiline) are Type B selective. bBlockade of pre-synaptic α-adrenergic receptors removes inhibition of serotonin and norepinephrine release. cBlockade of post-synaptic 5HT2A and 5HT2C-receptors removes inhibition of dopamine and norepinephrine release from the post-synaptic neuron. Journal of Pain and Symptom Management 2012 44, 763-783DOI: (10.1016/j.jpainsymman.2012.09.001) Copyright © 2012 Terms and Conditions

Fig. 2 Overview of the management of depression.30,99 aSub-threshold symptoms=patients with <5 DSM IV symptoms required for a diagnosis of depression. bCBT=cognitive behavioral therapy. cSee below, managing an inadequate initial response. Journal of Pain and Symptom Management 2012 44, 763-783DOI: (10.1016/j.jpainsymman.2012.09.001) Copyright © 2012 Terms and Conditions