Effectiveness of 23-Valent Polysaccharide Pneumococcal Vaccine and Changes in Invasive Pneumococcal Disease Incidence from 2000 to 2017 in Those Aged.

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Effectiveness of 23-Valent Polysaccharide Pneumococcal Vaccine and Changes in Invasive Pneumococcal Disease Incidence from 2000 to 2017 in Those Aged 65 and Over in England and Wales  Abdelmajid Djennad, Mary E. Ramsay, Richard Pebody, Norman K. Fry, Carmen Sheppard, Shamez N. Ladhani, Nick J. Andrews  EClinicalMedicine  DOI: 10.1016/j.eclinm.2018.12.007 Copyright © 2018 Terms and Conditions

Fig. 1 Vaccine effectiveness by time since vaccination using the spline model and a linear decline. Individual estimates for each year are also shown but are based on small numbers within each year. EClinicalMedicine DOI: (10.1016/j.eclinm.2018.12.007) Copyright © 2018 Terms and Conditions

Fig. 2 Corrected trends in the elderly IPD incidence in England and Wales from 2000/01 to 2016/17. EClinicalMedicine DOI: (10.1016/j.eclinm.2018.12.007) Copyright © 2018 Terms and Conditions