Volume 15, Issue 3, Pages (March 2018)

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Presentation transcript:

Volume 15, Issue 3, Pages 369-375 (March 2018) A novel algorithm increases the delivery of effective cardiac resynchronization therapy during atrial fibrillation: The CRTee randomized crossover trial Christopher J. Plummer, PhD, FRCP, Christopher M. Frank, MD, Zsolt Bári, MD, Yahya S. Al Hebaishi, MD, Ruth Nicholson Klepfer, PhD, Robert W. Stadler, PhD, Subham Ghosh, PhD, Shufeng Liu, MS, Suneet Mittal, MD, FHRS Heart Rhythm Volume 15, Issue 3, Pages 369-375 (March 2018) DOI: 10.1016/j.hrthm.2017.10.026 Copyright © 2017 The Authors Terms and Conditions

Figure 1 Flow diagram for the study design. AF = atrial fibrillation; CRT = cardiac resynchronization therapy. Heart Rhythm 2018 15, 369-375DOI: (10.1016/j.hrthm.2017.10.026) Copyright © 2017 The Authors Terms and Conditions

Figure 2 Flow diagram for the EffectivCRT during AF (eCRTAF) algorithm. AF = atrial fibrillation. Heart Rhythm 2018 15, 369-375DOI: (10.1016/j.hrthm.2017.10.026) Copyright © 2017 The Authors Terms and Conditions

Figure 3 Cohort distribution of study participants. Heart Rhythm 2018 15, 369-375DOI: (10.1016/j.hrthm.2017.10.026) Copyright © 2017 The Authors Terms and Conditions

Figure 4 Effect of treatment (EffectivCRT during AF [eCRTAF]) on percent ventricular pacing (% V pacing) (left), % effective CRT pacing (middle), and mean heart rate (right). Light blue bars indicate control (Conducted AF Response [CAFR]). Dark blue bars indicate eCRTAF. Error bars indicate standard deviation. AF = atrial fibrillation; CRT = cardiac resynchronization therapy. Heart Rhythm 2018 15, 369-375DOI: (10.1016/j.hrthm.2017.10.026) Copyright © 2017 The Authors Terms and Conditions

Figure 5 Results subgrouped by percent ventricular pacing (%Vp) under control (top), % effective CRT (middle), and mean heart rate (bottom). Light blue bars indicate control (Conducted AF Response [CAFR]). Dark blue bars indicate EffectivCRT During AF (eCRTAF). Error bars indicate standard deviation. Heart Rhythm 2018 15, 369-375DOI: (10.1016/j.hrthm.2017.10.026) Copyright © 2017 The Authors Terms and Conditions