Chronic sinusitis in severe asthma is related to sputum eosinophilia

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Presentation transcript:

Chronic sinusitis in severe asthma is related to sputum eosinophilia Anneke ten Brinke, MDa,d, Diana C. Grootendorst, MSca, Judith Th. Schmidt, MD, PhDb, Francisca T. de Bruïne, MD, PhDc, Mark A. van Buchem, MD, PhDc, Peter J. Sterk, MD, PhDa, Klaus F. Rabe, MD, PhDa, Elisabeth H. Bel, MD, PhDa Journal of Allergy and Clinical Immunology Volume 109, Issue 4, Pages 621-626 (April 2002) DOI: 10.1067/mai.2002.122458 Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 1 Prevalence of nasal symptoms (left) and asthma symptoms (right) in severely asthmatic patients with extensive sinus disease (filled bars) versus those without sinus disease (open bars) . Error bars represent SEM (*P < .05). Journal of Allergy and Clinical Immunology 2002 109, 621-626DOI: (10.1067/mai.2002.122458) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 2 Relationship between sinus CT-scan score and level of eosinophils in peripheral blood (upper panel) , eosinophils in induced sputum (middle panel) , and NO in exhaled air (lower panel) in patients with severe asthma. Journal of Allergy and Clinical Immunology 2002 109, 621-626DOI: (10.1067/mai.2002.122458) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 3 Relationship between sinus CT-scan score and level of FRC (upper panel) and KCO (lower panel) in patients with adult-onset severe asthma. Journal of Allergy and Clinical Immunology 2002 109, 621-626DOI: (10.1067/mai.2002.122458) Copyright © 2002 Mosby, Inc. Terms and Conditions