MicroRNA Regulation of Stem Cell Fate

Slides:

Advertisements

Similar presentations

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

Advertisements

Bone Marrow-Derived Cell Therapy Stimulates Endogenous Cardiomyocyte Progenitors and Promotes Cardiac Repair Francesco S. Loffredo, Matthew L. Steinhauser,

Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells David J. Wong, Helen Liu, Todd W. Ridky, David Cassarino, Eran Segal, Howard.

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.

CDK Inhibitors: Cell Cycle Regulators and Beyond Arnaud Besson, Steven F. Dowdy, James M. Roberts Developmental Cell Volume 14, Issue 2, Pages

Myc Represses Primitive Endoderm Differentiation in Pluripotent Stem Cells Keriayn N. Smith, Amar M. Singh, Stephen Dalton Cell Stem Cell Volume 7, Issue.

Normal and Leukemic Stem Cell Niches: Insights and Therapeutic Opportunities Koen Schepers, Timothy B. Campbell, Emmanuelle Passegué Cell Stem Cell Volume.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Quantitative Single-Cell Approaches to Stem Cell Research Martin Etzrodt, Max Endele, Timm Schroeder Cell Stem Cell Volume 15, Issue 5, Pages (November.

Stem Cell Maintenance of the Mammary Gland: It Takes Two

Martin Wahlestedt, David Bryder Cell Stem Cell

Linking miRNA Regulation to BCR-ABL Expression: The Next Dimension

Volume 1, Issue 1, Pages (June 2007)

MicroRNA-124: Micromanager of Neurogenesis

Laetitia Seguin, Sara M. Weis, David A. Cheresh Cell Stem Cell

Cell Cycle Rules Pluripotency

Why Myc? An Unexpected Ingredient in the Stem Cell Cocktail

A Time to Divide: Does the Circadian Clock Control Cell Cycle?

Alessandra Pasut, Michael A. Rudnicki Cell Stem Cell

Surveillance for Secure Differentiation

Volume 9, Issue 2, Pages (August 2011)

Cellular Origin of Androgen Receptor Pathway-Independent Prostate Cancer and Implications for Therapy W. Nathaniel Brennen, John T. Isaacs Cancer Cell

Natalia J. Martinez, Richard I. Gregory Cell Stem Cell

Portrait of a Stem Cell Developmental Cell

Volume 26, Issue 1, Pages 1-2 (July 2014)

Eun-Jung Jung, George A. Calin Cancer Cell

Regulating Cancer Stem Cells the miR Way

Haunting the HOXA Locus: Two Faces of lncRNA Regulation

Wing Y. Chang, William L. Stanford Cell Stem Cell

Guillaume Richard-Carpentier, Guy Sauvageau Cell Stem Cell

Stem Cell Therapies in Clinical Trials: Progress and Challenges

Cellular Origin of Androgen Receptor Pathway-Independent Prostate Cancer and Implications for Therapy W. Nathaniel Brennen, John T. Isaacs Cancer Cell

Compacting Chromatin to Ensure Muscle Satellite Cell Quiescence

Why Myc? An Unexpected Ingredient in the Stem Cell Cocktail

HSPCs Get Their Motors Running for Asymmetric Fate Choice

TRRAP and the Maintenance of Stemness in Gliomas

BMP Signaling Goes Posttranscriptional in a microRNA Sort of Way

CHD7 in Charge of Neurogenesis

Tim Willinger, Richard A. Flavell Cell Stem Cell

MicroRNAs in Tfh Cells: Micromanaging Inflammaging

MicroRNAs and Parallel Stem Cell Lives

The Importance of Timing

HMGA2, MicroRNAs, and Stem Cell Aging

Enhanc(er)ing Skin Stem Cells

Mohammad Abdul-Ghani, Lynn A. Megeney Cell Stem Cell

Meddling with METTLs in Normal and Leukemia Stem Cells

Powering Reprogramming with Vitamin C

Volume 6, Issue 3, Pages (March 2010)

Hematopoietic Stem Cells in Transit— Where's the Niche?

Heterochronic Genes and the Nature of Developmental Time

Ee-chun Cheng, Haifan Lin Developmental Cell

Polycomb Repression under the Skin

Long Noncoding RNAs in Cell-Fate Programming and Reprogramming

HSC Fate Is Tethered to Mitochondria

MicroRNAs Make a Difference in Cardiovascular Robustness

The Side Story of Stem-like Glioma Cells

Volume 22, Issue 4, Pages (April 2018)

ADARs Edit MicroRNAs to Promote Leukemic Stem Cell Activity

Guillermo A. Orsi, Monica Naughtin, Geneviève Almouzni Cell Stem Cell

Using Notches to Track Mammary Epithelial Cell Homeostasis

Stem Cells Neuron Volume 46, Issue 3, Pages (May 2005)

Mesp1 at the Heart of Mesoderm Lineage Specification

A Host MicroRNA Brokers Truce with HSV-1

Ye-Guang Chen, Zhongwei Li, Xiao-Fan Wang Cell Stem Cell

Special Stem Cells for Bone

Of Mice and Man: Differential DNMT Dependence in Mammalian ESCs

Knocking the Wnt out of the Sails of Leukemia Stem Cell Development

Presentation transcript:

MicroRNA Regulation of Stem Cell Fate Qintong Li, Richard I. Gregory Cell Stem Cell Volume 2, Issue 3, Pages 195-196 (March 2008) DOI: 10.1016/j.stem.2008.02.008 Copyright © 2008 Elsevier Inc. Terms and Conditions

Figure 1 Potential Roles of Different miRNAs in Embryonic Stem Cell Self-Renewal and Differentiation (A) Though not essential for ES cell viability, miRNAs are important for normal cell-cycle progression and stem cell proliferation. The particular miRNA or miRNAs important for this regulation have yet to be defined. (B) The developmentally regulated let-7 family miRNAs promote stem cell differentiation and may act by repressing expression of the self-renewal machinery. (C) miR-1 and miR-133 do not initiate ES cell differentiation but rather direct cell fate choices through the repression of alternative cell lineage gene expression. Cell Stem Cell 2008 2, 195-196DOI: (10.1016/j.stem.2008.02.008) Copyright © 2008 Elsevier Inc. Terms and Conditions