REFLEX and REFLEXION study design.

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Nat. Rev. Neurol. doi: /nrneurol

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Presentation transcript:

REFLEX and REFLEXION study design. REFLEX and REFLEXION study design. Short arrows indicate conversion to CDMS and the consequent switch to open-label treatment, which could happen at any time throughout the study. CDMS, clinically definite multiple sclerosis; IFN, interferon; MS, multiple sclerosis; qw, once weekly; REFLEX, REbif FLEXible dosing in early MS; REFLEXION, REbif FLEXible dosing in early MS extension; sc, subcutaneous; tiw, three times weekly. Giancarlo Comi et al. J Neurol Neurosurg Psychiatry 2017;88:285-294 ©2017 by BMJ Publishing Group Ltd