Outcomes post cardiac surgery in patients treated with fenoldopam vs dopamine End point Fenoldopam, n (%) Dopamine, n (%) p Acute renal failure (25% increase in serum creatinine from baseline) 17 (42.5) 16 (40) 0.9 Renal replacement therapy 4 (10) Death 3 (7.5) 0.5 Bove T et al Circulation 2005; 111:3230-3235.
Outcomes with fenoldopam vs placebo in patients with acute tubular necrosis End point Fenoldopam, n (%) Placebo, n (%) p Dialysis therapy and/or death at 21 days 22 (27.5) 29 (38.7) 0.235 Dialysis therapy 13 (16.25) 19 (25.3) 0.163 Death at 21 days (%) 13.8 25.3 0.068 Tumlin JA et al. Am J Kidney Dis 2005; 46:26-34. .