Allogeneic Stem Cell Transplantation in Congenital Hemoglobinopathies Using a Tailored Busulfan-Based Conditioning Regimen: Single-Center Experience

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Presentation transcript:

Allogeneic Stem Cell Transplantation in Congenital Hemoglobinopathies Using a Tailored Busulfan-Based Conditioning Regimen: Single-Center Experience Irina Zaidman, Jacob M. Rowe, Abdalla Khalil, Myriam Ben-Arush, Ronit Elhasid Biology of Blood and Marrow Transplantation Volume 22, Issue 6, Pages 1043-1048 (June 2016) DOI: 10.1016/j.bbmt.2016.03.003 Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Survival function. (A) Rate of 5-year overall survival for thalassemia patients after first transplantation was 90.5% ± 5.3%. (B) Rate of 5-year event-free survival (thalassemia-free survival) was 81.7% ± 6.8%. (C) Overall survival of patients receiving stem cells from related donors (MSDs and MFDs) compared with unrelated donors, 96.6% ± 3.4% versus 53.3% ± 24.8%, respectively (P = .005). Biology of Blood and Marrow Transplantation 2016 22, 1043-1048DOI: (10.1016/j.bbmt.2016.03.003) Copyright © 2016 The American Society for Blood and Marrow Transplantation Terms and Conditions