Nat. Rev. Cardiol. doi: /nrcardio

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Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.1 Figure 9 3D modelling of the aortic valve from computed tomography data Figure 9 | 3D modelling of the aortic valve from computed tomography data. a | Reconstructed aortic cusp images at mid-diastole (closed; left) and mid-systole (open; right) used to calculate the surface of the individual cusps and sinus of Valsalva. b | Differences in cusp surface areas and coapted surface areas in a normal individual, a patient with aortic root dilatation with competent aortic valve (ARD AR–), and a patient with aortic root dilatation and aortic regurgitation (ARD AR+). Aortic cusp remodelling (enlargement) is more pronounced in patients with aortic root dilatation compared with normal individuals, and is greatest in patients with aortic regurgitation (AR). In addition, patients with AR show asymmetry of the aortic root. L, left; LCC, left coronary cusp; N, noncoronary; NCC, noncoronary cusp; R, right; RCC, right coronary cusp. Reproduced from Kim, D. H. et al. Aortic valve adaptation to aortic root dilatation: insights into the mechanism of functional aortic regurgitation from 3-dimensional cardiac computed tomography. Circ. Cardiovasc. Imaging. 7, 828–835 (2014), with permission from Wolters Kluwer Health, Inc. Reproduced from Kim, D. H. et al. Aortic valve adaptation to aortic root dilatation: insights into the mechanism of functional aortic regurgitation from 3-dimensional cardiac computed tomography. Circ. Cardiovasc. Imaging. 7, 828–835 (2014), with permission from Wolters Kluwer Health, Inc. Bax, J. J. & Delgado, V. (2017) Advanced imaging in valvular heart disease Nat. Rev. Cardiol. doi:10.1038/nrcardio.2017.1