Jaime Céspedes, MD, German Briceño, MD, MSc, Michael E

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Targeting Preschool Children to Promote Cardiovascular Health: Cluster Randomized Trial Jaime Céspedes, MD, German Briceño, MD, MSc, Michael E. Farkouh, MD, MSc, Rajesh Vedanthan, MD, MPH, Jorge Baxter, MA, Martha Leal, MD, MSc, Paolo Boffetta, MD, PhD, Mark Woodward, MSc, Marilyn Hunn, Rodolfo Dennis, MD, MSc, Valentin Fuster, MD, PhD The American Journal of Medicine Volume 126, Issue 1, Pages 27-35.e3 (January 2013) DOI: 10.1016/j.amjmed.2012.04.045 Copyright © 2013 Terms and Conditions

Figure 1 Enrollment, randomization, and follow-up of study population. *(PF) = preschool facilities. The American Journal of Medicine 2013 126, 27-35.e3DOI: (10.1016/j.amjmed.2012.04.045) Copyright © 2013 Terms and Conditions

Figure 2 Changes in knowledge, attitudes, and habits in children (A), parents (B), and teachers (C), over the 18-month study period. Mean values correspond to the weighted total score (WTS). The WTS assumes differential weights to knowledge, attitudes, and habits (70, 20, 10, respectively). *During this period of time, the initial control group received an 8-month intervention. †Statistical significance of changes obtained between baseline and 6-month measurements. ‡Statistical significance of changes obtained between 6- and 18-month measurements. §Population with data available for all 3 measurements. The American Journal of Medicine 2013 126, 27-35.e3DOI: (10.1016/j.amjmed.2012.04.045) Copyright © 2013 Terms and Conditions

Figure 3 Distribution of children by nutritional status at baseline and 6-month and 18-month follow-ups. BMI = body mass index. The American Journal of Medicine 2013 126, 27-35.e3DOI: (10.1016/j.amjmed.2012.04.045) Copyright © 2013 Terms and Conditions

Figure 4 Program to prospectively evaluate the long-term knowledge, attitudes, and habits longitudinally in Spain. BMI = body mass index. The American Journal of Medicine 2013 126, 27-35.e3DOI: (10.1016/j.amjmed.2012.04.045) Copyright © 2013 Terms and Conditions