Dysbiosis of gut microbiota patterns in Chinese patients with IBD

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Dysbiosis of gut microbiota patterns in Chinese patients with IBD Dysbiosis of gut microbiota patterns in Chinese patients with IBD. (A) Comparison of Shannon index values between HC, CD, and UC groups. Dysbiosis of gut microbiota patterns in Chinese patients with IBD. (A) Comparison of Shannon index values between HC, CD, and UC groups. (B) Taxa listed according to their linear discriminant analysis (LDA) values determined from comparisons between the HC and IBD groups as computed by the use of the LEfSe algorithm. (C) Taxa illustrated according to their taxonomic relationship using a cladogram, showing the discriminative patterns in taxonomic lineages. The LDA cutoff values for panels A and B were set at 3.5. (D) Heat map showing abundance distributions for the 18 operational taxonomic units (OTUs) identified as key variables using the Kruskal-Wallis test (after Bonferroni correction) among the HC, CD, and UC groups. Lachnospiraceae OTUs are colored in green, and those of Ruminococcaceae are colored in red. (E) Weighted UniFrac PCoA data showing grouping patterns of HC, CD, and UC. Each dot represents a sample, with shapes indicating groups and colors the abundance of Clostridiales. Youlian Zhou et al. mSystems 2018; doi:10.1128/mSystems.00188-17