Elbasvir/Grazoprevir plus Sofosbuvir ± Ribavirin in Treatment-naive and Treatment-experienced Patients with Hepatitis C Virus Genotype 3 Infection and.

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Presentation transcript:

Elbasvir/Grazoprevir plus Sofosbuvir ± Ribavirin in Treatment-naive and Treatment-experienced Patients with Hepatitis C Virus Genotype 3 Infection and Compensated Cirrhosis: The C-ISLE Study

Disclosures and ACKNOWLEDGMENTS

BACKGROUND

AIM

C-ISLE: A randomized, open-label, UK-based clinical trial in gT3-INFECTED cirrhotics

Patients and Methods

Patient Demographics

SVR12 (FAS)

SVR12 (mFAS)

Non-SVR Patients

GT3 NS5A RAVs: Prevalence and impact on SVR12

Response in Y93H positive patients (>15%)

Adverse Events (AEs)

Conclusions