Cerebrospinal Fluid Markers of Brain Injury, Inflammation, and Blood-Brain Barrier Dysfunction in Cardiac Surgery Björn Reinsfelt, MD, PhD, Sven-Erik.

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Presentation transcript:

Cerebrospinal Fluid Markers of Brain Injury, Inflammation, and Blood-Brain Barrier Dysfunction in Cardiac Surgery Björn Reinsfelt, MD, PhD, Sven-Erik Ricksten, MD, PhD, Henrik Zetterberg, MD, PhD, Kaj Blennow, MD, PhD, Johan Fredén-Lindqvist, MD, Anne Westerlind, MD, PhD The Annals of Thoracic Surgery Volume 94, Issue 2, Pages 549-555 (August 2012) DOI: 10.1016/j.athoracsur.2012.04.044 Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Individual data on the intraoperative occurrence of microembolic signals. (CPB = cardiopulmonary bypass.) The Annals of Thoracic Surgery 2012 94, 549-555DOI: (10.1016/j.athoracsur.2012.04.044) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 (A)-(E) Individual data on preoperative and postoperative levels of the cerebrospinal fluid (CSF) to (A) serum albumin ratio, (B) interleukin-6 (IL-6), (C) interleukin-8 (IL-8), (D) S-100B, and (E) glial fibrillary acidic protein (GFAP). The Annals of Thoracic Surgery 2012 94, 549-555DOI: (10.1016/j.athoracsur.2012.04.044) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Individual data on preoperative and postoperative levels of the cerebrospinal fluid (CSF): (A) neuron-specific enolase (NSE), (B) total tau (T-tau), and (C) neurofilament light chain protein (NF-L). The Annals of Thoracic Surgery 2012 94, 549-555DOI: (10.1016/j.athoracsur.2012.04.044) Copyright © 2012 The Society of Thoracic Surgeons Terms and Conditions