Volume 82, Issue 3, Pages (August 2012)

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Volume 82, Issue 3, Pages 344-351 (August 2012) Composition and plaque patterns of coronary culprit lesions and clinical characteristics of patients with chronic kidney disease  Keiji Kono, Hideki Fujii, Kentaro Nakai, Shunsuke Goto, Junya Shite, Ken-ichi Hirata, Masafumi Fukagawa, Shinichi Nishi  Kidney International  Volume 82, Issue 3, Pages 344-351 (August 2012) DOI: 10.1038/ki.2012.118 Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 1 Compositional pattern of coronary culprit lesions. (a) Coronary plaque morphology of the culprit lesion. HD, hemodialysis. Vs. eGFR (ml/min per 1.73m2) ≥60, *P<0.05. Virtual Histology-Intravascular Ultrasound images of coronary culprit plaque. eGFR (ml/min per 1.73m2) (b) ≥60, (c) 30–60, and (d) <30, and (e) hemodialysis group. Green, fibrous; yellow, fibro fatty; red, necrotic core; white, dense calcium. eGFR, estimated glomerular filtration rate. Kidney International 2012 82, 344-351DOI: (10.1038/ki.2012.118) Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 2 Necrotic core (NC)/dense calcium (DC) ratio in the coronary culprit lesion. eGFR, estimated glomerular filtration rate; HD, hemodialysis. Vs. eGRF (ml/min per 1.73m2) ≥60, *P<0.05. Kidney International 2012 82, 344-351DOI: (10.1038/ki.2012.118) Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 3 Comparison of necrotic core (NC)/dense calcium (DC) ratio among different types of coronary artery disease (CAD) in all the study patients. AMI, acute myocardial infarction; SAP, stable angina pectoris; UAP, unstable angina pectoris. Vs. SAP, *P<0.05. Kidney International 2012 82, 344-351DOI: (10.1038/ki.2012.118) Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 4 Comparison of necrotic core (NC)/dense calcium (DC) ratio among different types of coronary artery disease in each group stratified by renal function. AMI, acute myocardial infarction; eGFR, estimated glomerular filtration rate; HD, hemodialysis; SAP, stable angina pectoris; UAP, unstable angina pectoris. Kidney International 2012 82, 344-351DOI: (10.1038/ki.2012.118) Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 5 Maximal arc of calcium deposit in the culprit lesion. HD, hemodialysis. Vs. eGFR (ml/min per 1.73m2) ≥60: aP<0.05 vs. 30≤ eGFR<60: bP<0.05. eGFR, estimated glomerular filtration rate. Kidney International 2012 82, 344-351DOI: (10.1038/ki.2012.118) Copyright © 2012 International Society of Nephrology Terms and Conditions

Figure 6 Study population flowchart. CABG, coronary artery bypass graft; eGFR, estimated glomerular filtration rate; HD, hemodialysis; PCI, percutaneous coronary intervention. Kidney International 2012 82, 344-351DOI: (10.1038/ki.2012.118) Copyright © 2012 International Society of Nephrology Terms and Conditions