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Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2016.96 Figure 2 Endoscopic images of a colonic lesion completely excised using the ESD technique Figure 2 | Endoscopic images of a colonic lesion completely excised using the ESD technique. a | A sigmoid polyp early cancer located close to ureterosigmoid anastomosis. b | Optical imaging revealed a central area of slight crypt distortion but intact vascular structures (arrow; Kudo type Vi, NICE classification type 2). c | At dissection a feeding vessel (arrow) was seen penetrating the muscle layer. d | Post-resection defect after ESD using a ball-tipped FlushKnife (Fujifilm, Japan). ESD, endoscopic submucosal dissection; NICE, Narrow-Band Imaging International Colorectal Endoscopic. Saunders, B. P. & Tsiamoulos, Z. P. (2016) Endoscopic mucosal resection and endoscopic submucosal dissection of large colonic polyps Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2016.96