M. Micaëlo, A. Goubard, G. La Ruche, E. Denamur, O. Tenaillon, E

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Molecular epidemiology of penicillinase-producing Neisseria gonorrhoeae isolates in France  M. Micaëlo, A. Goubard, G. La Ruche, E. Denamur, O. Tenaillon, E. Cambau, H. Jacquier, B. Bercot  Clinical Microbiology and Infection  Volume 23, Issue 12, Pages 968-973 (December 2017) DOI: 10.1016/j.cmi.2017.04.010 Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 1 Phylogenetic tree of concatenated porB and tbpB sequences of PPNG isolates. Each isolate is annotated with its ID number, its region of origin (NW, North West; NE, North-East; SW, South West; SE, South-East; PA, Paris Area), the TEM mutation (WT = wild type), and NG-MAST ST. The main STs and clusters (ST8922 and ST1285, cluster A and cluster B) are highlighted with light colors. Isolates harbouring an Asian plasmid are boxed in red, a Toronto/Rio plasmid in green, and an African plasmid with a TEM variant in black. The non-boxed isolates harbour an African plasmid associated with TEM-1. The TEM variants are indicated with the following symbols: □: P14L, ▪: P14S, ∗: M182T, ●: G228S, ○: Q269K. Clinical Microbiology and Infection 2017 23, 968-973DOI: (10.1016/j.cmi.2017.04.010) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Fig. 2 Distributions of penicillinase-producing N. gonorrhoeae isolates in France, by region. Clinical Microbiology and Infection 2017 23, 968-973DOI: (10.1016/j.cmi.2017.04.010) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions