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Volume 7, Issue 1, Pages 65-71 (January 2010) RR-interval irregularity precedes ventricular fibrillation in ST elevation acute myocardial infarction Miguel E. Lemmert, MD, Mohamed Majidi, MD, Mitchell W. Krucoff, MD, Sebastiaan C.A.M. Bekkers, MD, Harry J.G.M. Crijns, MD, PhD, FHRS, Hein J.J. Wellens, MD, PhD, FHRS, Andrzej S. Kosinski, PhD, Anton P.M. Gorgels, MD, PhD, FHRS Heart Rhythm Volume 7, Issue 1, Pages 65-71 (January 2010) DOI: 10.1016/j.hrthm.2009.09.024 Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 1 RR-interval irregularity (RRI) in ventricular fibrillation (VF) patient (A) and matched control patient (B). Primarily due to irregular runs of ventricular ectopic beats, the VF patient had an RRI of 257 ms prior to the ischemic VF (red arrow), whereas the control patient had an RRI of 20 ms in the equivalent time interval. Green complexes indicate sinus beats; red complexes indicate ventricular ectopic beats; blue complexes indicate artifact (not used for any calculations). Heart Rhythm 2010 7, 65-71DOI: (10.1016/j.hrthm.2009.09.024) Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 2 Sensitivity and specificity for all cutoff values for RR-interval irregularity (RRI). Heart Rhythm 2010 7, 65-71DOI: (10.1016/j.hrthm.2009.09.024) Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 3 Sensitivity and specificity for all cutoff values for the ST deviation score (STdev). Heart Rhythm 2010 7, 65-71DOI: (10.1016/j.hrthm.2009.09.024) Copyright © 2010 Heart Rhythm Society Terms and Conditions