In Vitro Mitral Valve Simulator Mimics Systolic Valvular Function of Chronic Ischemic Mitral Regurgitation Ovine Model Andrew W. Siefert, MS, Jean Pierre.

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In Vitro Mitral Valve Simulator Mimics Systolic Valvular Function of Chronic Ischemic Mitral Regurgitation Ovine Model Andrew W. Siefert, MS, Jean Pierre M. Rabbah, BS, Kevin J. Koomalsingh, MD, Steven A. Touchton, BS, Neelakantan Saikrishnan, PhD, Jeremy R. McGarvey, MD, Robert C. Gorman, MD, Joseph H. Gorman, MD, Ajit P. Yoganathan, PhD The Annals of Thoracic Surgery Volume 95, Issue 3, Pages 825-830 (March 2013) DOI: 10.1016/j.athoracsur.2012.11.039 Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 (A) Geometric map of ultrasonomicrometry crystals localized to the A2 anterior leaflet and mitral annulus (AC = anterior commissure; PC = posterior commissure.) (B) In vivo image of crystals localized to the mitral annulus and anterior leaflet with directions of strain shown. The Annals of Thoracic Surgery 2013 95, 825-830DOI: (10.1016/j.athoracsur.2012.11.039) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 (A) Mitral valve simulator with components identified. (B) Atrial echocardiographic image of mitral valve closure during peak systole within the simulator. The Annals of Thoracic Surgery 2013 95, 825-830DOI: (10.1016/j.athoracsur.2012.11.039) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions