Fig. 1. Bacterial communities shift during AD disease progression.

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Fig. 1. Bacterial communities shift during AD disease progression. Bacterial communities shift during AD disease progression. (A) Objective SCORAD for patients at baseline (n = 5), flare, and post-flare (n = 11). Higher SCORAD corresponds to more severe disease. ***P < 0.001, with nonparametric Wilcoxon rank-sum test. (B) Mean Shannon diversity ± SEM in controls and AD disease states. Colors correspond to disease state. Vf, volar forearm; Ic, inguinal crease; Fh, forehead; Oc, occiput; Ra, retroauricular crease. (C) Shannon diversity versus objective SCORAD for AcPc of AD patients. Pearson partial correlation (adjusting for disease state). (D) Mean relative abundance of bacterial genera in AcPc for controls and AD disease states. (E) Mean relative abundance of predominant genera in AcPc for disease states. Statistical significance based on paired Wilcoxon test and Bonferroni correction. F, flare; PF, post-flare. (F) Proportion of Staphylococcus versus objective SCORAD for AcPc of AD patients. Pearson partial correlation (adjusting for disease state). Allyson L. Byrd et al., Sci Transl Med 2017;9:eaal4651 Published by AAAS