Technical Solutions The Final Results Securing high efficiency genes engaged to the isoprenoids precursors pathway The small quantity of Isoprenoids products in nature from lack of limited precursors. The insufficiency of genomic network information about diverse biosynthesis pathways for producing multiform precursors. The reduced productivity due to growth inhibition by over-producing of various precursors. Technical Solutions The Final Results Construction of heterologous MVA pathway modules systems in E.coli Genome integration of optimized MVA pathway modules in E.coli Analysis and control of Isoprenoids biosynthsis pathway network in recombinant E.coli Isopentenyl pyrophosphate (IPP) The problems of Isoprenoids and other materials production in microbial organism Development of the module system for producing high efficiency Isoprenoids precursors. Identification of Isoprenoids biosynthsis pathway network in E.coli by introducing heterologous mevalonate pathway Optimization of Isoprenoids producing biosynthtic pathway in E.coli through control of genome expression levels and network analysis Optimization of MVA downstream pathway modules by synthetic promoter and RBS engineering Construction of Isoprenoids precursors producing conditions for the scale-up systems. Application of hetelogous MVA pathway in the carotenoids and ginsenoside biosynthsis patthways Optimization of MVA upstream pathway modules by synthetic promoter and ribosome binding site(RBS) engineering