US and European Perspectives on Sinusoidal Obstruction Syndrome

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Presentation transcript:

US and European Perspectives on Sinusoidal Obstruction Syndrome

Overview

Overview (cont)

Overview (cont)

Risk Assessment: CIBMTR VOD Risk Model

CIBMTR VOD Risk Model

Age and Risk of VOD/SOS

Conditioning Regimen and Risk of VOD/SOS

Observed VOD/SOS Among 4 Risk Groups

Preventing SOS

New EBMT Criteria for Diagnosing SOS/VOD in Adults

New EBMT Criteria for Diagnosing SOS/VOD in Adults (cont)

New EBMT Criteria for Severity Grading of Suspected SOS/VOD in Adults

EBMT Guidelines for Managing SOS/VOD

EBMT Guidelines for Managing SOS/VOD (cont)

Adverse Events Associated With Defibrotide in the International Compassionate Use Program

Other Measures for Treating SOS/VOD

Other Measures for Treating SOS/VOD (cont)

Summary

Abbreviations

Abbreviations (cont)

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