Immunohistochemical cellular characteristics.

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Presentation transcript:

Immunohistochemical cellular characteristics. Immunohistochemical cellular characteristics. Hepatocellular carcinoma (HCC) with marked cytoplasmic positivity for platelet-derived growth factor receptor alpha polypeptide (PDGFRα) of the tumour cells (A). Hepatocellular adenoma (HCA) with slight cytoplasmic positivity for PDGFRα of the tumour cells (B). HCC with marked cytoplasmic positivity for laminin of the tumour cells (C). HCC with neoplastic tissue negative and a marked cytoplasmic positivity for laminin in the sinusoidal lining (D). HCC with moderate cytoplasmic positivity for CD29 of the tumour cells (E). HCA with neoplastic tissue negative for CD29 (F). HCC with marked nuclear staining for B-cell-specific Moloney murine leukaemia virus integration site 1 (Bmi-1) with slight cytoplasmic positivity of the tumour cells (G). HCA with slight nuclear positivity for Bmi-1 of the tumour cells (H). K19, keratin 19. Renee G van Sprundel et al. Vet Rec Open 2017;4:e000212 ©2017 by British Veterinary Association