Gut Transit Is Associated With Gastrointestinal Symptoms and Gut Hormone Profile in Patients With Cirrhosis  Evangelos Kalaitzakis, Riadh Sadik, Jens Juul Holst, Lena Öhman, Einar Björnsson  Clinical Gastroenterology and Hepatology  Volume 7, Issue 3, Pages 346-352 (March 2009) DOI: 10.1016/j.cgh.2008.11.022 Copyright © 2009 AGA Institute Terms and Conditions

Figure 1 Frequency of transit abnormalities in patients with liver cirrhosis (black bars, n = 42) and healthy controls (white bars, n = 83). Reference values were based on percentiles 10 and 90 of the transit values of the healthy controls (n = 83).27,29 *P < .05; **P < .005. Clinical Gastroenterology and Hepatology 2009 7, 346-352DOI: (10.1016/j.cgh.2008.11.022) Copyright © 2009 AGA Institute Terms and Conditions

Figure 2 Median (half IQR) postprandial (A) glucose, (B) insulin, (C) leptin, and (D) ghrelin profiles in patients with cirrhosis (solid line, n = 25) and healthy controls (dashed line, n = 10). In multivariate repeated-measures analysis of variance, the effect of group was significant (P < .05) for glucose, insulin, and ghrelin. The effect of time was significant (P < .05) for glucose, insulin, and leptin, and the effect of group-time interaction was significant (P < .05) for glucose. Analysis of leptin data as the ratio leptin/BMI yielded similar results. *P < .05, **P < .005 between patients with cirrhosis and healthy controls. Clinical Gastroenterology and Hepatology 2009 7, 346-352DOI: (10.1016/j.cgh.2008.11.022) Copyright © 2009 AGA Institute Terms and Conditions

Figure 3 Median (half IQR) postprandial (A) GLP-1 and (B) PYY levels in patients with cirrhosis (solid line, n = 25) and healthy controls (dashed line, n = 10). In multivariate repeated-measures analysis of variance, the effect of time was significant (P < .05) for GLP-1 and PYY. The effect of group-time interaction was significant (P < .05) for GLP-1 only. *P < .05, **P < .005 between patients with cirrhosis and healthy controls. Clinical Gastroenterology and Hepatology 2009 7, 346-352DOI: (10.1016/j.cgh.2008.11.022) Copyright © 2009 AGA Institute Terms and Conditions