The EGLN-HIF O2-Sensing System: Multiple Inputs and Feedbacks

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The EGLN-HIF O2-Sensing System: Multiple Inputs and Feedbacks Mircea Ivan, William G. Kaelin Molecular Cell Volume 66, Issue 6, Pages 772-779 (June 2017) DOI: 10.1016/j.molcel.2017.06.002 Copyright © 2017 Terms and Conditions

Figure 1 Model of Cooperation between Coding Genes and miR-210 Downstream of HIF1 Feedback loop leading to renormalization of local O2 tension as a result of decreased local consumption. Molecular Cell 2017 66, 772-779DOI: (10.1016/j.molcel.2017.06.002) Copyright © 2017 Terms and Conditions

Figure 2 Model of Noncoding RNA-Based Feedback Circuits Optimizing the Transition from an HIF1- to an HIF2-Based Hypoxic Response Molecular Cell 2017 66, 772-779DOI: (10.1016/j.molcel.2017.06.002) Copyright © 2017 Terms and Conditions