Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study  Radhika K Ailawadi, M.D., Smeeta Jobanputra,

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Presentation transcript:

Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study  Radhika K Ailawadi, M.D., Smeeta Jobanputra, M.D., Meera Kataria, M.D., Bilgin Gurates, M.D., Serdar E Bulun, M.D.  Fertility and Sterility  Volume 81, Issue 2, Pages 290-296 (February 2004) DOI: 10.1016/j.fertnstert.2003.09.029

FIGURE 1 Pre- and post-treatment disease stages, based on ASRM endometriosis scores, for individual patients (n = 10). (A) Baseline: first-look laparoscopy 1 month before treatment; (B) one-month post-treatment: second-look laparoscopy 1 month after treatment. Determinations for each patient before and after treatment are interconnected. Ailawadi. Letrozole effects on endometriosis. Fertil Steril 2004. Fertility and Sterility 2004 81, 290-296DOI: (10.1016/j.fertnstert.2003.09.029)

FIGURE 2 (A) Baseline (1 month pretreatment) and, (B) 1-month post-treatment pain scores for individual patients (n = 10). Determinations for each patient before and after treatment are interconnected. Ailawadi. Letrozole effects on endometriosis. Fertil Steril 2004. Fertility and Sterility 2004 81, 290-296DOI: (10.1016/j.fertnstert.2003.09.029)

FIGURE 3 Pre- and post-treatment DEXA scan results for bone density in the hip and spine of individual patients (n = 10). (A) hip; (B) spine. Determinations for each patient (numbered) before and after treatment are interconnected. A slight but statistically significant improvement in hip bone density (P = .04) was noted. No statistically significant difference was detected between groups with respect to spine bone density. Ailawadi. Letrozole effects on endometriosis. Fertil Steril 2004. Fertility and Sterility 2004 81, 290-296DOI: (10.1016/j.fertnstert.2003.09.029)