Phosphoinositide Function in Cytokinesis

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Phosphoinositide Function in Cytokinesis Julie A. Brill, Raymond Wong, Andrew Wilde  Current Biology  Volume 21, Issue 22, Pages R930-R934 (November 2011) DOI: 10.1016/j.cub.2011.10.001 Copyright © 2011 Elsevier Ltd Terms and Conditions

Figure 1 Inositol phospholipids and regulatory enzymes important for cytokinesis. A schematic diagram showing the metabolic relationships among the different PIPs involved in cytokinesis. PI pathway regulators, including lipid kinases (red) and phosphatases (blue), are indicated. Current Biology 2011 21, R930-R934DOI: (10.1016/j.cub.2011.10.001) Copyright © 2011 Elsevier Ltd Terms and Conditions

Figure 2 Potential targets of regulation by PIPs during cytokinesis. A model of the cleavage furrow showing PIPs, PIP pathway enzymes and potential PIP targets involved in cytokinesis. Question marks refer to unknowns discussed in the text. The model is a compilation of observations drawn from studies in multiple systems, and not all steps necessarily function in a single organism. Current Biology 2011 21, R930-R934DOI: (10.1016/j.cub.2011.10.001) Copyright © 2011 Elsevier Ltd Terms and Conditions