Sweet NETs, Bitter Wounds Venizelos Papayannopoulos  Immunity  Volume 43, Issue 2, Pages 223-225 (August 2015) DOI: 10.1016/j.immuni.2015.08.002 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Increased NETosis Suppresses Wound Healing in Diabetes High circulating glucose concentrations are associated with upregulation of PAD4 and an increase in NET release in response to unknown signals in the skin. NETs are proposed to form in higher numbers in the wounds of patients with diabetes and result in slower wound reepithelialization and healing. Immunity 2015 43, 223-225DOI: (10.1016/j.immuni.2015.08.002) Copyright © 2015 Elsevier Inc. Terms and Conditions