Researchers Find Their Nemo

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Researchers Find Their Nemo Anthony King Cell Volume 139, Issue 5, Pages 843-846 (November 2009) DOI: 10.1016/j.cell.2009.11.019 Copyright © 2009 Elsevier Inc. Terms and Conditions

Figure 1 The Zebrafish in Close Up (Top) BRAFV600E is the most common oncogene in human melanomas. Zebrafish carrying mutant p53 and expressing a BRAFV600E transgene in melanophore pigment cells develop melanomas. (Middle) In the zebrafish casper mutant, development of pigment cells is disrupted. These optically clear fish are valuable for imaging studies as their internal organs are visible. (Bottom) Zebrafish embryos expressing a fluorescent protein in their primordial germ cells. Photos courtesy of C. Ceol (top), R.M. White (middle), and P. Schlueter and R. Peterson (bottom). Cell 2009 139, 843-846DOI: (10.1016/j.cell.2009.11.019) Copyright © 2009 Elsevier Inc. Terms and Conditions