Todd C. Crawford, MD, J. Trent Magruder, MD, Joshua C

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Presentation transcript:

Impaired Renal Function Should Not Be a Barrier to Transplantation in Patients With Cystic Fibrosis Todd C. Crawford, MD, J. Trent Magruder, MD, Joshua C. Grimm, MD, Alejandro Suarez-Pierre, MD, Xun Zhou, MD, Jinny S. Ha, MD, Robert S. Higgins, MD, Stephen R. Broderick, MD, Jonathan B. Orens, MD, Pali Shah, MD, Christian A. Merlo, MD, Bo S. Kim, MD, Errol L. Bush, MD The Annals of Thoracic Surgery Volume 104, Issue 4, Pages 1231-1236 (October 2017) DOI: 10.1016/j.athoracsur.2017.05.032 Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan-Meier survival analysis comparing survival out to 5 years after lung transplantation in patients with cystic fibrosis (CF) with and without pretransplantation renal dysfunction (PRD) (GFR ≤60 mL/min). (CI = confidence interval.) The Annals of Thoracic Surgery 2017 104, 1231-1236DOI: (10.1016/j.athoracsur.2017.05.032) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Kaplan-Meier analysis of graft survival at 5 years after lung transplantation in patients with cystic fibrosis (CF) with and without pretransplantation renal dysfunction (PRD) (GFR ≤60 mL/min). (CI = confidence interval.) The Annals of Thoracic Surgery 2017 104, 1231-1236DOI: (10.1016/j.athoracsur.2017.05.032) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Kaplan-Meier analysis comparing probability of prolonged hospitalization (>25 days) after lung transplantation in patients with CF with and without pretransplantation renal dysfunction (PRD) (GFR ≤60 mL/min). (CI = confidence interval.) The Annals of Thoracic Surgery 2017 104, 1231-1236DOI: (10.1016/j.athoracsur.2017.05.032) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Supplemental Figure 1 Multivariable logistic regression model identifying independent factors associated with 1-year mortality (left). Covariate hazard ratios with associated 95% confidence intervals displayed graphically (right). The Annals of Thoracic Surgery 2017 104, 1231-1236DOI: (10.1016/j.athoracsur.2017.05.032) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Supplemental Figure 2 Multivariable logistic regression model identifying independent factors associated with 3-year mortality (left). Covariate hazard ratios with associated 95% confidence intervals displayed graphically (right). The Annals of Thoracic Surgery 2017 104, 1231-1236DOI: (10.1016/j.athoracsur.2017.05.032) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

Supplemental Figure 3 Multivariable logistic regression model identifying independent factors associated with 5-year survival (left). Covariate hazard ratios with associated 95% confidence intervals displayed graphically (right). The Annals of Thoracic Surgery 2017 104, 1231-1236DOI: (10.1016/j.athoracsur.2017.05.032) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions