Accounting for Linkage in Family-Based Tests of Association with Missing Parental Genotypes Eden R. Martin, Meredyth P. Bass, Elizabeth R. Hauser, Norman L. Kaplan The American Journal of Human Genetics Volume 73, Issue 5, Pages 1016-1026 (November 2003) DOI: 10.1086/378779 Copyright © 2003 The American Society of Human Genetics Terms and Conditions
Figure 1 Power of the APL test, PDT, and FBAT over 1,000 replicate data sets of N AAU families, without data from parents, and 1,000 replicate data sets of combined samples of 250 AA and 250 AAU families, without data from parents. Power is computed for significance level (α) of 0.05 and 0.001 for recessive and multiplicative models. The American Journal of Human Genetics 2003 73, 1016-1026DOI: (10.1086/378779) Copyright © 2003 The American Society of Human Genetics Terms and Conditions