The 3-compartment lung model described by Riley and Cournand151,152 represents gas exchange in the lung in regard to the matching of alveolar gas volume.

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The 3-compartment lung model described by Riley and Cournand151,152 represents gas exchange in the lung in regard to the matching of alveolar gas volume (V̇A) and perfusion (Q̇T), shunt (Q̇S), and dead space (VD). The 3-compartment lung model described by Riley and Cournand151,152 represents gas exchange in the lung in regard to the matching of alveolar gas volume (V̇A) and perfusion (Q̇T), shunt (Q̇S), and dead space (VD). The ideal compartment represents areas of perfect alveolar gas volume to Q̇T matching. The pure shunt compartment represents areas of perfusion without ventilation. The pure dead-space compartment represents areas of ventilation with no perfusion. The sum of the regions of alveolar dead space (VDalv) and anatomic dead space (VDanat) equal the physiologic dead space (VDphys). The dead space fraction is equal to VDphys divided by tidal volume (VT). Also shown are PaCO2, the partial pressure of venous carbon dioxide (PvCO2), the relationship between PaCO2 and minute CO2 production (V̇CO2) and alveolar gas volume, the partial pressure of mixed alveolar carbon dioxide (PACO2), the partial pressure of end-tidal carbon dioxide (PETCO2), and the PĒCO2 in relation to the model and the volumetric capnogram. From Reference 116. Mark S Siobal Respir Care 2016;61:1397-1416 (c) 2012 by Daedalus Enterprises, Inc.