Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens Hiba Bashir, MD, Kristine Grindle, BS, Rose Vrtis, BS,

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Presentation transcript:

Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens Hiba Bashir, MD, Kristine Grindle, BS, Rose Vrtis, BS, Fue Vang, BS, Teresa Kang, BS, Lisa Salazar, BS, Elizabeth Anderson, RN, Tressa Pappas, BS, Ronald Gangnon, PhD, Michael D. Evans, MS, Daniel J. Jackson, MD, Robert F. Lemanske, MD, Yury A. Bochkov, PhD, James E. Gern, MD Journal of Allergy and Clinical Immunology Volume 141, Issue 2, Pages 822-824.e9 (February 2018) DOI: 10.1016/j.jaci.2017.09.027 Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Association of viral detection with clinical outcomes. Detection of RV species in weekly samples was compared to contemporaneous reports of cold symptom scores (A), asthma symptom scores (B), and risk for exacerbation of asthma (C). Points and lines represent means and 95% CIs. Mult., Multiple. *P < .05 vs no virus; #P < .05 vs RV-B. Journal of Allergy and Clinical Immunology 2018 141, 822-824.e9DOI: (10.1016/j.jaci.2017.09.027) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Association of RV species with quantity of bacterial pathogens. Mult., Multiple. Journal of Allergy and Clinical Immunology 2018 141, 822-824.e9DOI: (10.1016/j.jaci.2017.09.027) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Risk of respiratory illnesses associated with detection of individual or multiple (“Mult”) RV species. The OR was calculated as the risk of detecting RV-A, RV-B, RV-C, or Mult RV species during a period of illness compared with a period of equal length during which no respiratory illness symptoms were reported. Journal of Allergy and Clinical Immunology 2018 141, 822-824.e9DOI: (10.1016/j.jaci.2017.09.027) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Effects of age on the prevalence of bacterial pathogen detection. Journal of Allergy and Clinical Immunology 2018 141, 822-824.e9DOI: (10.1016/j.jaci.2017.09.027) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions