Association Between Level of Hepatitis D Virus RNA at Week 24 of Pegylated Interferon Therapy and Outcome  Onur Keskin, Heiner Wedemeyer, Ali Tüzün, Kalliopi Zachou, Xheni Deda, George N. Dalekos, Benjamin Heidrich, Selcen Pehlivan, Stefan Zeuzem, Kendal Yalçın, Selim Gürel, Fehmi Tabak, Ramazan Idilman, Hakan Bozkaya, Michael Manns, Cihan Yurdaydin  Clinical Gastroenterology and Hepatology  Volume 13, Issue 13, Pages 2342-2349.e2 (December 2015) DOI: 10.1016/j.cgh.2015.05.029 Copyright © 2015 Terms and Conditions

Figure 1 A significant difference was observed in (A) HDV RNA and (B) quantitative HBsAg levels throughout the treatment and post-treatment follow-up period between post-treatment week 24 virologic responders vs nonresponders to pegylated interferon treatment. tx, treatment. Clinical Gastroenterology and Hepatology 2015 13, 2342-2349.e2DOI: (10.1016/j.cgh.2015.05.029) Copyright © 2015 Terms and Conditions

Figure 2 End-of-treatment virologic response to treatment prediction based on on-treatment week 24 (A) HDV RNA detectability and (B) quantitative HBsAg decrease. (A) Four patients had missing HDV RNA data and (B) 5 patients had missing quantitative HBsAg levels. End-of-treatment virologic null response to treatment prediction based on cut-off values of (C) 1 and (E) 2 log decreases of on-treatment week 24 HDV RNA, and (D) combined use of HDV RNA and HBsAg decrease. Clinical Gastroenterology and Hepatology 2015 13, 2342-2349.e2DOI: (10.1016/j.cgh.2015.05.029) Copyright © 2015 Terms and Conditions

Figure 3 Post-treatment week 24 virologic response to treatment prediction based on on-treatment week 24 HDV RNA and quantitative HBsAg levels. In 3 patients HDV RNA data were missing. Clinical Gastroenterology and Hepatology 2015 13, 2342-2349.e2DOI: (10.1016/j.cgh.2015.05.029) Copyright © 2015 Terms and Conditions

Supplementary Figure 1 Flow diagram of patient numbers at baseline, end of treatment, and end of follow-up period. Clinical Gastroenterology and Hepatology 2015 13, 2342-2349.e2DOI: (10.1016/j.cgh.2015.05.029) Copyright © 2015 Terms and Conditions