Breakthrough Cancer Pain: An Observational Study of 1000 European Oncology Patients  Andrew Davies, FRCP, Alison Buchanan, BSc, Giovambattista Zeppetella, FRCP, Josep Porta-Sales, MD, Rudolf Likar, MD, Wolfgang Weismayr, MD, Ondrej Slama, MD, Tarja Korhonen, MD, Marilene Filbet, MD, Philippe Poulain, MD, Kyriaki Mystakidou, MD, Alexandros Ardavanis, MD, Tony O’Brien, FRCPI, Pauline Wilkinson, FRCP, Augusto Caraceni, MD, Furio Zucco, MD, Wouter Zuurmond, MD, Steen Andersen, MD, Anette Damkier, MD, Tove Vejlgaard, MSc, Friedemann Nauck, MD, Lukas Radbruch, MD, Karl-Fredrik Sjolund, MD, Mariann Stenberg, MD  Journal of Pain and Symptom Management  Volume 46, Issue 5, Pages 619-628 (November 2013) DOI: 10.1016/j.jpainsymman.2012.12.009 Copyright © 2013 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Diagnostic algorithm used to identify patients with breakthrough pain (adapted from Davies et al.3). Journal of Pain and Symptom Management 2013 46, 619-628DOI: (10.1016/j.jpainsymman.2012.12.009) Copyright © 2013 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 2 Time to peak intensity. BTcP = breakthrough cancer pain. Journal of Pain and Symptom Management 2013 46, 619-628DOI: (10.1016/j.jpainsymman.2012.12.009) Copyright © 2013 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 3 Duration of untreated episodes. BTcP = breakthrough cancer pain. Journal of Pain and Symptom Management 2013 46, 619-628DOI: (10.1016/j.jpainsymman.2012.12.009) Copyright © 2013 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 4 Box and whisker plot showing lower quartile, median, upper quartile, and range of values for interference with various aspects of daily living. Journal of Pain and Symptom Management 2013 46, 619-628DOI: (10.1016/j.jpainsymman.2012.12.009) Copyright © 2013 U.S. Cancer Pain Relief Committee Terms and Conditions