P. Cantù, L. Claut, A. Elvevi, I. Parzanese, M. Maggioni, D. Conte, R

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Can biliary endoscopy play a role in liver disease associated to cystic fibrosis? P. Cantù, L. Claut, A. Elvevi, I. Parzanese, M. Maggioni, D. Conte, R. Penagini, C. Colombo Journal of Cystic Fibrosis Volume 14, Issue 5, Pages E21-E23 (September 2015) DOI: 10.1016/j.jcf.2015.06.006 Copyright © 2015 European Cystic Fibrosis Society. Terms and Conditions

Fig. 1 Magnetic resonance cholangiography showed a short biliary stricture (arrow) with retrodilation of the left hepatic duct. Journal of Cystic Fibrosis 2015 14, E21-E23DOI: (10.1016/j.jcf.2015.06.006) Copyright © 2015 European Cystic Fibrosis Society. Terms and Conditions

Fig. 2 Liver biopsy, histopathologic pictures. A. Portal space with mild inflammation and focal intrabiliary granulocytes, suggestive of cholangitis (H&E 200×). B. Liver parenchyma with diffuse canalicular cholestasis (H&E 200×). C. Central venule with mild perivenular and perisinusoidal fibrosis (Masson-Trichrome 200×). D. Immunostaining for Cytocheratin 7 highlights periportal ductular proliferation and biliary metaplasia (200×). Journal of Cystic Fibrosis 2015 14, E21-E23DOI: (10.1016/j.jcf.2015.06.006) Copyright © 2015 European Cystic Fibrosis Society. Terms and Conditions

Fig. 3 Endocopic retrograde cholangiopancreatography. A. Biliary stricture of the left hepatic duct (arrow). B. 10 Fr multistenting was performed. Journal of Cystic Fibrosis 2015 14, E21-E23DOI: (10.1016/j.jcf.2015.06.006) Copyright © 2015 European Cystic Fibrosis Society. Terms and Conditions