Blood Pressure Control in Continuous Flow Left Ventricular Assist Devices: Efficacy and Impact on Adverse Events Brent C. Lampert, DO, Chad Eckert, PhD,

Slides:

Advertisements

Similar presentations

Heart Transplant vs Left Ventricular Assist Device in Heart Transplant-Eligible Patients Matthew L. Williams, MD, Jaimin R. Trivedi, MD, MPH, Kelly C.

Advertisements

Fenton H. McCarthy, MD, Dale Kobrin, BA, J. Eduardo Rame, MD, Peter W

Management of Anticoagulation in Patients with Mechanical Circulatory Support Using a Physician-Based Versus a Pharmacist Directed Anticoagulation Clinic-Based.

Obese Patients and Mechanical Circulatory Support: Weight Loss, Adverse Events, and Outcomes Firas Zahr, MD, Elizabeth Genovese, MS, Michael Mathier,

Wenrui Ma, MD, Wei Zhang, MD, Wei Shi, MD, Ye Kong, MD, Xinyu Ma, MS

Survival on the Heart Transplant Waiting List: Impact of Continuous Flow Left Ventricular Assist Device as Bridge to Transplant Jaimin R. Trivedi, MD,

Michael W. A. Chu, MD, Kapil Sharma, MD, Christo I

Robert L. Smith, MD, Morley A. Herbert, PhD, Todd M

Louis A. Brunsting, MD, Robert S. Binford, MD, Kimberly C

Berlin Heart EXCOR Ventricular Assist Device: Multilayer Membrane Rupture in a Pediatric Patient Arianna Di Molfetta, PhD, Sergio Filippelli, PhD, Gianfranco.

Laura Harvey, MD, Christopher Holley, MD, Samit S

Jiro Esaki, MD, PhD, Bradley G. Leshnower, MD, Jose N

Inhaled Nitric Oxide Plus Iloprost in the Setting of Post-Left Assist Device Right Heart Dysfunction Theofani Antoniou, MD, PhD, Christos Prokakis, MD,

Incidence and Patterns of Adverse Event Onset During the First 60 Days After Ventricular Assist Device Implantation Elizabeth A. Genovese, BS, Mary Amanda.

Bi-Ventricular Circulatory Support With the Abiomed AB5000 System in a Patient With Idiopathic Refractory Ventricular Fibrillation Li Zhang, MD, MS,

Severity of Preoperative Aortic Regurgitation Does Not Impact Valve Durability of Aortic Valve Repair Following the David V Valve Sparing Aortic Root.

Implantable Continuous-Flow Right Ventricular Assist Device: Lessons Learned in the Development of a Cleveland Clinic Device Kiyotaka Fukamachi, MD,

Obese Patients and Mechanical Circulatory Support: Weight Loss, Adverse Events, and Outcomes Firas Zahr, MD, Elizabeth Genovese, MS, Michael Mathier,

Impact of Preoperative Angiotensin-Converting Enzyme Inhibitor Use on Clinical Outcomes After Cardiac Surgery Maral Ouzounian, MD, Karen J. Buth, MS,

Surgical Ventricular Restoration for Advanced Congestive Heart Failure: Should Pulmonary Hypertension Be a Contraindication? Nishant D. Patel, BA, Jason.

Javed Butler, MD, Carrie Geisberg, MD, Renee Howser, MSN, Peer M

Muhammad A. Mumtaz, MD, Roger B. B

Fenton H. McCarthy, MD, Dale Kobrin, BA, J. Eduardo Rame, MD, Peter W

Initial Clinical Experience With the Symphony Heart Assist System

John Alfred Carr, MD, Joseph J. Amato, MD, Robert S.D. Higgins, MD

Cardiac Resynchronization Therapy for the Failing Fontan Patient

Origins of the Cardiothoracic Surgery Network (CTSNet)

Who Do You Say You Are? The Annals of Thoracic Surgery

Expanding Indications for Valve-Sparing Aortic Root Reconstruction: Early and Midterm Results Johanna Valo, BM, Janne J. Jokinen, MD, PhD, Markku Kaarne,

Allen Cheng, MD, Erin M. Schumer, MD, MPH, Jaimin R

Continuous-Flow Left Ventricular Assist Device Implantation in Patients With a Small Left Ventricle Masashi Kawabori, MD, Chitaru Kurihara, MD, Tadahisa.

Left Ventricular Assist Device Inflow Angle and Pump Positional Change Over Time Adverse Impact on Left Ventricular Assist Device Function Toshinobu.

Extracorporeal Membrane Oxygenation for Advanced Refractory Shock in Acute and Chronic Cardiomyopathy Christian A. Bermudez, MD, Rodolfo V. Rocha, MD,

Discussions in Cardiothoracic Treatment and Care: Mechanical Circulatory Support Left Ventricular Assist Device Therapy for Patients With Advanced Heart.

Maria Kalliopi Konstantinidou, MD, PhD, Neil Moat, MD, PhD

Should Patients 60 Years and Older Undergo Bridge to Transplantation With Continuous-Flow Left Ventricular Assist Devices? Jeremiah G. Allen, MD, Arman.

Surgical management of valvular disease in patients requiring left ventricular assist device support Vivek Rao, MD, PhD, James P Slater, MD, Niloo M.

Nicholas A. Haglund, MD, Mary E. Davis, MS, CCRP, Nicole M

Brian A. Bruckner, MD, Limael E

Low-Dose Prophylactic Intravenous Immunoglobulin Does Not Prevent HLA Sensitization in Left Ventricular Assist Device Recipients Stavros G. Drakos, MD,

Freddy Vermeulen, MD, Ben Swinkels, MD, Wim Jan van Boven, MD

Hybrid Management of a Giant Left Main Coronary Artery Aneurysm

Percutaneous Transcatheter Closure of the Aortic Valve

Right Heart Dysfunction After Left Ventricular Assist Device Implantation: A Comparison of the Pulsatile HeartMate I and Axial-Flow HeartMate II Devices

John F. Lazar, MD, Michael F. Swartz, PhD, Matthew P

Embolized Methyl Methacrylate to the Right Atrium After Kyphoplasty

Robert W. Emery, MD, Christopher C. Krogh, Kit V. Arom, MD, PhD, Ann M

Erik N. Sorensen, PhD, Richard N. Pierson, MD, Erika D

Editorial Board, January 2010

Sarah C. Huen, MD, Chirag R. Parikh, MD, PhD

Ayesha S. Bryant, MSPH, William L. Holman, MD, Navin C

Early Outcomes With Marginal Donor Hearts Compared With Left Ventricular Assist Device Support in Patients With Advanced Heart Failure Erin M. Schumer,

Jay K. Bhama, MD, Utsav Bansal, BS, Daniel G. Winger, MS, Jeffrey J

Sequential Design for Clinical Trials Evaluating a Prosthetic Heart Valve Cody Hamilton, PhD, Michael Lu, PhD, Steven Lewis, PhD, William Anderson, PhD

Is severe right ventricular failure in left ventricular assist device recipients a risk factor for unsuccessful bridging to transplant and post-transplant.

A Target for Perioperative Blood Pressure During Cardiac Operations

Farhan Zafar, MD, John L. Jefferies, MD, MPH, Christine J

Cerebrovascular accidents in patients with a ventricular assist device

Late Aortic Insufficiency Related to Poor Prognosis During Left Ventricular Assist Device Support Koichi Toda, MD, PhD, Tomoyuki Fujita, MD, Keitaro.

Comparing Aortic Root Replacements: Porcine Bioroots Versus Pericardial Versus Mechanical Composite Roots: Hemodynamic and Ventricular Remodeling at Greater.

Y. Joseph Woo, MD, Michael A. Acker, MD The Annals of Thoracic Surgery

Use of Ventricular Assist Devices in Children Across the United States: Analysis of 7.5 Million Pediatric Hospitalizations David L.S. Morales, MD, Farhan.

Bicuspid Aortic Insufficiency With Aortic Root Aneurysm: Root Reimplantation Versus Bentall Root Replacement Prashanth Vallabhajosyula, MD, Wilson Y.

Ventricular Assist Device Implant in the Elderly Is Associated With Increased, but Respectable Risk: A Multi-Institutional Study Pavan Atluri, MD, Andrew.

Influence of Prosthesis–Patient Mismatch on Diastolic Heart Failure After Aortic Valve Replacement Shahab Nozohoor, MD, Johan Nilsson, MD, PhD, Carsten.

The Impact of New Technology on Cardiothoracic Surgical Practice

Marginal Donor Use in Patients Undergoing Heart Transplantation With Left Ventricular Assist Device Explantation Marat Fudim, MD, Mary E. Davis, MS,

Significance of Postoperative Acute Renal Failure After Continuous-Flow Left Ventricular Assist Device Implantation Jamil Borgi, MD, Athanasios Tsiouris,

Robert J. DiDomenico, PharmD, Malek G. Massad, MD

Michael O. Kayatta, MD, Bradley G

Presentation transcript:

Blood Pressure Control in Continuous Flow Left Ventricular Assist Devices: Efficacy and Impact on Adverse Events Brent C. Lampert, DO, Chad Eckert, PhD, Stephanie Weaver, CRNP, Ana Scanlon, PA, Kathy Lockard, RN, Carrie Allen, RN, Nicole Kunz, RN, Christian Bermudez, MD, Jay K. Bhama, MD, Michael A. Shullo, PharmD, Robert L. Kormos, MD, Mary Amanda Dew, PhD, Jeffrey J. Teuteberg, MD The Annals of Thoracic Surgery Volume 97, Issue 1, Pages 139-146 (January 2014) DOI: 10.1016/j.athoracsur.2013.07.069 Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Blood pressure (BP) measurement algorithm. (ACE = angiotensin-converting enzyme inhibitors; ARB = angiotensin II receptor blockers; Cr = creatinine; DBP = diastolic BP; HR = heart rate; K = potassium; RV = right ventricle; SBP = systolic BP.) The Annals of Thoracic Surgery 2014 97, 139-146DOI: (10.1016/j.athoracsur.2013.07.069) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Mean blood pressure over time: axial versus centrifugal flow devices. (LVAD = left ventricular flow device.) The Annals of Thoracic Surgery 2014 97, 139-146DOI: (10.1016/j.athoracsur.2013.07.069) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Mean flow over time: axial versus centrifugal flow devices. (LVAD = left ventricular flow device.) The Annals of Thoracic Surgery 2014 97, 139-146DOI: (10.1016/j.athoracsur.2013.07.069) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Mean blood pressure over time: by number of blood pressure medications. (CrCl = creatinine clearance.) The Annals of Thoracic Surgery 2014 97, 139-146DOI: (10.1016/j.athoracsur.2013.07.069) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Creatinine clearance (CrCl) over time: by number of blood pressure medications. The Annals of Thoracic Surgery 2014 97, 139-146DOI: (10.1016/j.athoracsur.2013.07.069) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Cumulative incidence of neurologic adverse events by number of antihypertensive medications. The Annals of Thoracic Surgery 2014 97, 139-146DOI: (10.1016/j.athoracsur.2013.07.069) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 7 Degree of aortic insufficiency pre-implantation and at the end of follow-up. The Annals of Thoracic Surgery 2014 97, 139-146DOI: (10.1016/j.athoracsur.2013.07.069) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 8 Freedom from greater than mild aortic insufficiency (AI). (BP = blood pressure; VAD = ventricular assist device.) The Annals of Thoracic Surgery 2014 97, 139-146DOI: (10.1016/j.athoracsur.2013.07.069) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions