Radiation Therapy for Cutaneous T-Cell Lymphomas

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Presentation transcript:

Radiation Therapy for Cutaneous T-Cell Lymphomas Daniel J. Tandberg, MD, Oana Craciunescu, PhD, Chris R. Kelsey, MD Dermatologic Clinics Volume 33, Issue 4, Pages 703-713 (October 2015) DOI: 10.1016/j.det.2015.05.006 Copyright © 2015 The Authors Terms and Conditions

Fig. 1 Medical linear accelerator used to generate and deliver external beam radiation therapy. Dermatologic Clinics 2015 33, 703-713DOI: (10.1016/j.det.2015.05.006) Copyright © 2015 The Authors Terms and Conditions

Fig. 2 Plot of percentage of radiation dose (%) versus depth (mm) for various electron beam energies from 6 to 22 MeV. Dermatologic Clinics 2015 33, 703-713DOI: (10.1016/j.det.2015.05.006) Copyright © 2015 The Authors Terms and Conditions

Fig. 3 Method of local electron beam radiation therapy to cutaneous lymphoma lesions. A margin is drawn around visible or palpable disease (A). A lead cutout is created conforming to the target volume (B). The patient is positioned on the treatment table and the electron beam therapy is delivered by a medical linear accelerator (C). Note the bolus material placed over the cutaneous lesion that ensures the maximum dose is delivered to the skin surface (arrow). Dermatologic Clinics 2015 33, 703-713DOI: (10.1016/j.det.2015.05.006) Copyright © 2015 The Authors Terms and Conditions

Fig. 4 The six treatment positions used for total skin electron beam therapy. (From Smith BD, Wilson LD. Management of mycosis fungoides. Part 2: treatment. Oncology 2003;17(10):1424; with permission.) Dermatologic Clinics 2015 33, 703-713DOI: (10.1016/j.det.2015.05.006) Copyright © 2015 The Authors Terms and Conditions

Fig. 5 Patient undergoing total skin electron beam therapy. Both internal eye and mouth shields are used. The hands and feet are shielded and treated separately with photon fields. Dermatologic Clinics 2015 33, 703-713DOI: (10.1016/j.det.2015.05.006) Copyright © 2015 The Authors Terms and Conditions

Fig. 6 Localized primary cutaneous anaplastic large cell lymphoma at diagnosis (A) and 3 months after radiation therapy (B). Dermatologic Clinics 2015 33, 703-713DOI: (10.1016/j.det.2015.05.006) Copyright © 2015 The Authors Terms and Conditions