Nat. Rev. Endocrinol. doi:10.1038/nrendo.2017.115 Figure 1 Hypothesized mechanisms underlying the effects of oxytocin on caloric intake Figure 1 | Hypothesized mechanisms underlying the effects of oxytocin on caloric intake. In response to peripheral signals that indicate energy availability, oxytocin acts on homeostatic, reward and impulse control brain circuitry to reduce caloric intake, particularly of more palatable foods. Lawson, E. A. (2017) The effects of oxytocin on eating behaviour and metabolism in humans Nat. Rev. Endocrinol. doi:10.1038/nrendo.2017.115