Effect of exogenous IL-6-related invasiveness of PSN-1 cells

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Effect of exogenous IL-6-related invasiveness of PSN-1 cells fig. 1 Effect of exogenous IL-6-related invasiveness of PSN-1 cells (in the lower chamber) cc/field * * * IL-6 *p<0.01 vs baseline

fig. 2 Effect of Celergen on the invasiveness behaviour of the two distinct clones subsets from PSN-1 n. of invading cc/field * ** C: Celergen; *p<0.01 vs LI cells; **p<0.01 vs untreated HI cells.

* ** Effect of Celergen on IL-6 content of conditioned medium ng/ml fig. 3 Effect of Celergen on IL-6 content of conditioned medium ng/ml * ** C: Celergen; *p<0.001 vs LCM cells; **p<0.01 vs untreated HCM

*p<0.001 vs LI cells; **p<0.01 vs untreated HI and LI cells. fig. 4 Effect of Celergen on IL-6 receptor expression in the two clones subsets from PSN-1 % of IL-6 expressing cc * ** ** untreated cells Celergen-treated cc HI LI *p<0.001 vs LI cells; **p<0.01 vs untreated HI and LI cells.

*p<0.001 vs untreated HI and LI cells. fig. 5 Effect of IL-6 100 ng/ml on HI and LI cells n. of invading cc/field * * *p<0.001 vs untreated HI and LI cells.

fig. 6-a Effect of HCM and Celergen-enriched HCM on HI and LI cells n. of invading cc/field * * ** ** *p<0.001 vs naive HI subset cells; **p<0.01 vs HCM or LCM only-treated cells.

fig. 6-b Effect of HCM and Celergen-enriched HCM on HI and LI cells n. of invading cc/field * ** * ** *p<0.001 vs naive LI subset cells; **p<0.01 vs HCM or LCM only-treated cells.