Childhood Infections Highly contagious Presentation in infancy or early childhood Relatively high incidence
“the fifth disease” 1 Measles (paramyxovirus) 2 Rubella (rubella virus) 3 Scarlatina (toxin of group A Streptococci) 4 Filatov - Dukes (rubella variant) 5 Erythema infectiosum (human Parvo B19) 6. Exanthema subitum (Human herpes virus type 6) (Roseola infantum)
Other childhood infections 1 Chickenpox Whooping cough, Diphtheria, Poliomyelitis, Tetanus Mumps RSV bronchiolitis Rota virus gastroenteritis Meningitis (different agents) Pneumococci, H.Influenza, Meningococci Enteroviruses, adenoviruses, papilloma viruses
Other childhood infections 2 Herpes viruses ► HSV 1 ► HSV 2 ► VZV (Varicella - Zoster virus) ► CMV (Cytomegalovirus) ► EBV (Epstein-Barr virus) ► HHV 6 (Human herpes virus type 6) ► HHV 8 (Human herpes virus type 8)
Incubation time and infectiousness Infection Incubation (d) contagious Measles 10-14 -2 till +4 after rash Chickenpox 10-21 -1 till last dried vesicle Parvo B19 7-12 -7 till +7 HHV6 10-15 -7 till +7 RSV 2-4 -3 till + 12 Rota 2-4 -3 till + 12
Measles exanthema
Koplik’s spots in measles
Chickenpox
Pneumonia caused by VZV
Shingles caused by VZV
Primary stomatitis by HSV 1
Cold sore (reactivation of primary HSV 1 stomatitis)
Encephalitis by HSV 1
Rubella exanthema
Skin after scarlet fever
Tetanus (Risus Sardonicus)
Neonatal tetanus (opisthotonus)
Smallpox (extinct)
Smallpox (extinct?)
Vaccination (Edward Jenner 1796 cowpox/ vaccinia)
Vaccination for Smallpox
Vaccination for Diphteria
Vaccination for Measles
Immunological Memory
Immune responses to viruses
Meningococcal septicemia
Mumps
Rota virus
Mollusca
What is your diagnosis?
Impetigo
What is your diagnosis?
….and the last slide