Effects of cancer treatment during pregnancy on fetal and child development Tineke Vandenbroucke, MSc, Magali Verheecke, MD, Monica Fumagalli, MD, Christianne.

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Effects of cancer treatment during pregnancy on fetal and child development Tineke Vandenbroucke, MSc, Magali Verheecke, MD, Monica Fumagalli, MD, Christianne Lok, PhD, Prof Frédéric Amant, PhD The Lancet Child & Adolescent Health Volume 1, Issue 4, Pages 302-310 (December 2017) DOI: 10.1016/S2352-4642(17)30091-3 Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 1 Fetal exposure to irradiation of the upper body parts The figure illustrates examples of brain, thyroid, and breast cancer. The highest dose of radiation is focused on the tumour (red solid lines), but scatter beams with low radiation dose (red dashed lines) divert away from the tumour. Curved black lines indicate abdominal shielding, and double arrows indicate the distance from the radiation field to the fundus. The Lancet Child & Adolescent Health 2017 1, 302-310DOI: (10.1016/S2352-4642(17)30091-3) Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 2 Fetal, neonatal, and long-term risks of systemic cancer treatment during pregnancy The Lancet Child & Adolescent Health 2017 1, 302-310DOI: (10.1016/S2352-4642(17)30091-3) Copyright © 2017 Elsevier Ltd Terms and Conditions