Cytokine gene polymorphisms in northern Indian women with recurrent miscarriages Farah Parveen, M.Sc., Anju Shukla, M.D., Suraksha Agarwal, Ph.D. Fertility and Sterility Volume 99, Issue 2, Pages 433-440.e2 (February 2013) DOI: 10.1016/j.fertnstert.2012.09.025 Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions
Figure 1 Meta-analysis of (A) interleukin (IL) 6, (B) IL-10 (1082), and (C) interferon-γ. Odds ratio estimates with 95% confidence interval (CI), random-effect model. The size of the square is proportional to the percentage weight of each study; horizontal lines represent 95% CI. Fertility and Sterility 2013 99, 433-440.e2DOI: (10.1016/j.fertnstert.2012.09.025) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions
Figure 2 Classification and regression tree analysis analysis of genetic variants of proinflammatory and antiinflammatory pathway genes in modulating recurrent miscarriage risk. Mother node constitutes interleukin (IL) 10-1082A/T divided into two nodes: mutant and heterozygous (mutant and wild type). Wild type is attached to IL-1 RN8006 heteromutant and wild node is attached to IL-4 590C/T. This pathway, i.e., IL-10–IL-1–IL-4 is the protective pathway with moderate OR. Fertility and Sterility 2013 99, 433-440.e2DOI: (10.1016/j.fertnstert.2012.09.025) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions